نتایج جستجو برای: rabeprazole

تعداد نتایج: 497  

2017
E. Karabacak

this group. Although rare, anaphylactic reactions to PPIs have been described. They have modified benzimidazoles with a pyridine ring and chemically related structures A number of case reports suggesting cross-reactivity patterns among lansoprazole and rabeprazole, omeprazole and lansoprazole, and omeprazole and pantoprazole have been reported. Our patient had IgE-mediated anaphylactic or urtic...

2014
Kenji Furuta Yukie Kohata Yasuhiro Fujiwara Mitsushige Sugimoto Takahiro Uotani Mihoko Yamade Shu Sahara Hitomi Ichikawa Takahisa Furuta Kenta Nio Ryuichi Iwakiri Masahiko Inamori Osamu Kawamura Motoyasu Kusano Mototsugu Kato Noriyuki Kawami Katsuhiko Iwakiri Toshihisa Takeuchi Kazuhide Higuchi Masahito Aimi Kohji Naora Kazuma Fujimoto Tetsuo Arakawa Yoshikazu Kinoshita

Comparisons between the acid inhibitory effects of rabeprazole and esomeprazole after single oral administration with standard doses have not been previously presented. We examined intra-gastric pH after oral administrations of these two proton pump inhibitors using 24-h pH monitoring. Fifty-four normal volunteers not infected by Helicobacter pylori were investigated. Using a cross-over design,...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2010
Takeo Yasu Ryota Ikee Yoshiyuki Miyasaka Hideo Chubachi Shigeru Saito

After coronary stent implantation, dual-antiplatelet therapy (DAT), such as aspirin and clopidogrel, is essential to prevent stent thrombosis. Proton-pump inhibitors (PPIs) may be used to prevent gastrointestinal (GI) bleeding during DAT, but there is no evidence for the efficacy of PPIs in this setting. Because both clopidogrel and PPIs are metabolized by cytochrome P450 (CYP) 2C19, there is a...

2012
Nobuhiko Oridate Ryoji Tokashiki Yusuke Watanabe Aki Taguchi Osamu Kawamura Kazuma Fujimoto

Objective. To know the characteristics of endoscopic laryngeal and pharyngeal abnormalities in Japanese patients with laryngopharyngeal reflux symptoms (LPRS). Methods. A total of 146 endoscopic images of the larynx and pharynx (60 pairs for the rabeprazole group and 13 pairs for the control group) were presented to 15 otolaryngologists blinded to patient information and were scored according t...

Journal: :Chinese medical journal 2013
Hai-di Zhu Heng Wang Xian-ming Xia Shu-man Xu Yao Lan

BACKGROUND Several randomized controlled trials (RCTs) have compared endoscopic and symptomatic relapses in patients with erosive gastroesophageal reflux disease (GERD). We have summarized current evidence for rabeprazole 10 or 20 mg once daily for GERD maintenance treatment over 1 or 5 years. METHODS MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were searched, throu...

2010
A. H. M. Thippeswamy M. Sajjan M. B. Palkar B. C. Koti A. H. M. Viswanathaswamy

The present study was designed to compare ulcer protective effect of proton pump inhibitors viz. omeprazole, rabeprazole and lansoprazole against dexamethasone plus pylorus ligation induced ulcer model. Dexamethasone (5 mg/kg) was used as an ulcerogen. Dexamethasone suspended in 1% CMC in water was given orally to all the rats 15 min after the pylorus ligation. Omeprazole (20 mg/kg), rabeprazol...

2013
X. M. Xia H. Wang

Background. Randomized controlled trials (RCTs) have been conducted comparing the efficacy of rabeprazole 20 mg or omeprazole 20 mg once daily for patients with erosive gastroesophageal reflux disease (GERD). Until now, no study has synthesized all available data examining this issue. Method. Medline, Embase, and the Cochrane central register of controlled trials were searched (through December...

2010
Dimal A. Shah Kashyap K. Bhatt Sunil L. Baldania

A simple, sensitive and precise stability indicating HPLC method has been developed for the estimation of rabeprazole and itopride in combined dosage form. A Phenomenex Gemini C-18, 5 μm column with a mobile phase containing 0.02 M ammonium acetate (pH 6): acetonitrile: methanol (45: 20: 35, v/v/v) was used. The flow rate was 1.0 mL min and effluents were monitored at 284 nm. Rabeprazole and it...

2014
Irini Zouboulis-Vafiadis Emmanuel Paraskevas Dimitrios Tzourmakliotis Maria Hatzikyriakou Angeliki Mestoussi Vassilios Vasdekis Nikolaos Katsilabros Athanasios Arhimandritis Alexandra Papadokostopoulou

BACKGROUND Rabeprazole produces a profound and long-lasting inhibition of gastric acid secretion. The aim of the study was to monitor the safety and efficacy of rabeprazole administered to patients with erosive or symptomatic non-erosive reflux disease, in real-life healthcare settings. METHODS Male and female patients, aged ≥18 years, with endoscopy diagnosed GERD were included; patients rec...

2015
Necdet Fatih Yaşar Erdal Polat Mustafa Duman Meltem Dağdelen Mehmet Yalcın Gunal Orhan Uzun Cebrail Akyuz Kıvanc Derya Peker Sinan Yol

BACKGROUND/AIMS It has been reported that proton pump inhibitors induce relaxation in different types of smooth muscles. The aim of this study is to investigate in vitro effects of proton pump inhibitors on human pylorus muscle. METHODS Pyloric sphincters were studied in 10 patients who were operated for stomach cancer. In isolated organ bath, control and re-sponse to rabeprazole were recorde...

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