The concept of radiation-induced hormesis, whereby a low dose is beneficial and high detrimental, has been gaining attention in the fields molecular biology, environmental toxicology radiation biology. There growing body literature that recognises importance hormetic response not only field, but also with agents. However, there continuing debate on magnitude mechanism response, which could make...

Numerous organisms have shown an ability to survive and reproduce under low-dose ionizing radiation arising from natural background radiation or from nuclear accidents. In a literature review, we found a total of 17 supposed cases of adaptation, mostly based on common garden experiments with organisms only deriving from typically two or three sampling locations. We only found one experimental s...

On June 23, 2015, the US Nuclear Regulatory Commission (NRC) issued a formal notice in the Federal Register that it would consider whether "it should amend its 'Standards for Protection Against Radiation' regulations from the linear non-threshold (LNT) model of radiation protection to the hormesis model." The present commentary supports this recommendation based on the (1) flawed and deceptive ...

Professor Don Luckey identified the phenomenon of “radiation hormesis,” and he described it in a paper in the Health Physics Society Journal, in 1982. (He also authored two books on this subject.) CRIEPl initiated a research program on radiation hormesis following this publication to confirm, "Is it true or not?" After nearly ten years of research activities on data surveys and animal tests wit...

Current guidelines for cancer risk assessment emphasize a toxicant's "mode of action", rather than its empirically derived dose-response relationship, for determining whether linear low-dose extrapolation is appropriate. Thus, for reasons of policy, demonstration of hormesis is generally insufficient to justify a non-linear approach, although it may provide important insights into the actions o...

Today's radiation safety norms are based on the linear no-threshold theory (LNT): extrapolation of the dose-response relationships down to the minimal doses, where such relationships are unproven and can be inverse due to hormesis. The most promising way to obtaining reliable data on the dose-effect relationships for low radiation doses would be large-scale animal experiments. Outstanding publi...