Melanized microorganisms are often found in environments with very high background radiation levels such as in nuclear reactor cooling pools and the destroyed reactor in Chernobyl. These findings and the laboratory observations of the resistance of melanized fungi to ionizing radiation suggest a role for this pigment in radioprotection. We hypothesized that the radioprotective properties of mel...

The radioprotective effects of carnosic acid (CA), carnosol (COL), and rosmarinic acid (RO) against chromosomal damage induced by gamma-rays, compared with those of L-ascorbic acid (AA) and the S-containing compound dimethyl sulfoxide (DMSO), were determined by use of the micronucleus test for antimutagenic activity, evaluating the reduction in the frequency of micronuclei (MN) in cytokinesis-b...

the aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. the rats were treated with thymol at dose of 50 mg/kg before exposure to radiation at dose 15gy. salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

introduction it has long been known that ionizing radiation can lead to detrimental effects in normal cells. in this light, radioprotective chemicals have been used to decrease morbidity or mortality caused by ionizing irradiation. this study aimed to evaluate the radio-protective effect of n-acetylcysteineagainst radiation-induced mortality in male mice. materials and methods 52 healthy male m...

the present study investigated the radioprotective efficacy of lentil ( lens culinaris ) sprouts against x-ray radiation-induced cellular damage. lentil seeds were dark germinated at low temperature and the sprout extract was prepared in pbs. free radical scavenging of extract was evaluated using 2,2-diphenyl-1-picrylhydrazyl (dpph) assay and then the radioprotective potency of extract (0 to 10...

Herbal plants and products represent important source of natural antioxidant offer an alternative to synthetic protectors. Moringa oliefera, a herbal medicinal plant has been screen for their radioprotective activity. For the purpose study male Swiss albino mice were divided into seven groups. The exposed gamma radiation (2.5 Gy 5.0 Gy) also provided mercuric chloride (0.5 ppm) both separately ...

The radioprotective activity of Piper betel ethanolic extract (PE) has been studied using rat liver mitochondria and pBR 322 plasmid DNA as two model in vitro systems. The extract effectively prevented gamma-ray induced lipid peroxidation as assessed by measuring thiobarbituric acid reactive substrates, lipid hydroperoxide and conjugated diene. Likewise, it prevented radiation-induced DNA stran...