It is widely believed that the brain processes information and stores memories by modifying and stabilizing synaptic connections between neurons. In experimental models of synaptic plasticity, such as long-term potentiation (LTP), the stabilization of changes in synaptic strength requires rapid de novo RNA and protein synthesis. Candidate genes, which could underlie activity-dependent plasticit...

New gene expression is necessary for long-term potentiation (LTP) consolidation, yet roles for specific activity-induced mRNAs have not been defined. Here we probed the dynamic function of activity-induced Arc (activity-regulated cytoskeletal-associated protein)/Arg3.1 (activity-regulated gene 3.1 protein homolog) mRNA using brief, local infusions of antisense (AS) oligodeoxynucleotides at mult...

In a manner unique among activity-regulated immediate early genes (IEGs), mRNA encoded by Arc (also known as Arg3.1) undergoes rapid transport to dendrites and local synaptic translation. Despite this intrinsic appeal, relatively little is known about the neuronal and behavioral functions of Arc or its molecular mechanisms of action. Here, we attempt to distill recent advances on Arc spanning i...

Large Ra excesses in a number of mafic arc magmas, and geophysical observations of earthquake hypocenters locations, indicate that mafic melts can get transferred from source to surface within days to ~1 kyr. Decreasing Ra–Th disequilibria with increasing SiO2 in co-magmatic suites of individual arc volcanoes suggest that magma differentiation often occurs on timescales of a few thousand years ...

The rapid increase of non-linear loads in the last three decades has caused electrical quantities such as voltages and currents in 3-phase distribution systems to become distorted waveforms. This paper reviews, explains and discusses some new concepts, definitions and new available theory in the unbalanced and distorted systems. The usefulness of the proposed practical definitions is investigat...

The rapid increase of non-linear loads in the last three decades has caused electrical quantities such as voltages and currents in 3-phase distribution systems to become distorted waveforms. This paper reviews, explains and discusses some new concepts, definitions and new available theory in the unbalanced and distorted systems. The usefulness of the proposed practical definitions is investigat...

Currently, ultra-rapid orbits play an important role in the high-speed development of global navigation satellite system (GNSS) real-time applications. This contribution focuses on the impact of the fitting arc length of observed orbits and solar radiation pressure (SRP) on the orbit prediction performance for GPS, GLONASS, Galileo and BeiDou. One full year's precise ephemerides during 2015 wer...

Fluorescence microscopy requires high photon-flux densities in the specimen plane. These intensities are only achieved by lasers, arc lamps, and, most recently, light-emitting diodes (LEDs). Lasers and LEDs, however, are restricted to a limited number of wavelength regions, whereas with arc lamps it is possible to select arbitrary wavelengths and wavelength regions. Moreover, the lower cost of ...

Power quality is becoming a more concern of today’s power system engineer due to rapid growth of non-linear loads in distribution network. Electrical Arc Furnace (EAF) is one of the responsible causes for deteriorating power quality in the distribution network. Hence electric arc furnace model is needed to study and to analyze the power quality in the distribution network. This paper presents a...

We used a visual-search method to investigate the role of shadows in the rapid discrimination of scene properties. Targets and distractors were light or dark 2-D crescents of identical shape and size, on a mid-grey background. From the dark stimuli, illusory 3-D shapes can be created by blurring one arc of the crescent. If the inner arc is blurred, the stimulus is perceived as a curved surface ...