OBJECTIVE To evaluate the efficacy of furosemide for prevention of exercise-induced pulmonary hemorrhage (EIPH) in Thoroughbred racehorses under typical racing conditions. DESIGN Randomized, placebo-controlled, blinded, crossover field trial. ANIMALS 167 Thoroughbred racehorses. PROCEDURES Horses were allocated to race fields of 9 to 16 horses each and raced twice, 1 week apart, with each...

This article presents a methodology for acquisition and analysis of bright-field amplitude contrast image data in high-throughput screening (HTS) for the measurement of cell density, cell viability, and classification of individual cells into phenotypic classes. We present a robust image analysis pipeline, where the original data are subjected to image standardization, image enhancement, and se...

One hundred and seventy-four consecutive patients with symptoms of derangement of the knee were examined with an arthroscope under local anaesthesia using a continuous pressure-irrigation system. A 0.2 per cent prilocaine-saline solution was used as irrigation fluid. In the first 19 patients the serum level of prilocaine was monitored for six hours after the start of irrigation. Eighteen of the...

abstract background: despite advances in the field of intravenous therapy, phlebitis is still a common complication of peripheral venous catheter and finding an appropriate solution to prevent and reduce the incidence of this complication remains challenging. one of the methods used in reducing the incidence of phlebitis is the use of saline lock, which is forgotten in most hospitals. therefore...

Rectangular flaps on the rat or mouse dorsum are frequently used for flap survival elongation research. However, since rectangular flaps are purely random, the survival rate varies among individuals. A reliable animal flap model with low individual variation is desirable for flap survival research, especially in the angiogenic field. We investigated the survival rate of paired flaps in the rat ...

1. Rat soleus (SOL) and extensor digitorum longus (EDL) muscles, stored for 2-6hrs at 30•Ž in Krebs' solution with rat serum in higher concentration than 2%, showed low internal Na and high internal K concentrations as compared with control muscles stored in the normal saline solution. Such a serum effect on the EDL muscles decreased with lowering of temperature of the external solution. 2. The...

The present experiments were designed to find a method to facilitate methotrexate (MTX) transfer into rat brain tissue. Adult male Wistar-Kyoto strain rats, anesthetized with pentobarbital-Na, received an infusion of the drug solution to be tested into the right internal carotid artery (5 ml/min, 30 sec) 5 min before injection of MTX (7 mg/kg). After 10 min, the MTX levels in the cerebral hemis...

Serial determinations of plasma volume and urinary sodium excretion were determined during saluresis in 20 hypertensive patients. Although the diuretics produced a decrease in plasma volume and an increase in urinary sodium excretion in all patients, there was no direct relationship between the decrease in plasma volume and the fall in arterial pressure. Concomitant administration of dextran so...

A 48-year-old man who had a complaint of swelling in the left submandibular region and right side of the neck was referred to our radiology clinic for sonographic examination that revealed a type 1 hydatid cyst with a diameter of 32 mm in the left submandibular gland, and a type 3 hydatid cyst with a diameter of 33 mm in the right thyroid gland. The diagnosis was verified by computed tomography...

To assess nutrient sensitivity in a population of gastric load-sensitive vagal afferents, their neurophysiological activity was examined in anesthetized rats with inflated pyloric cuffs after gastric infusion of a range of volumes of nutrient and equiosmotic saline solutions. Responses to physiological saline loads (1, 2, 4, and 8 ml) were compared with responses elicited by the same volume ran...