dose-dependent pharmacokinetic of phenytoin necessitates the estimation of the maximum rate of metabolism (vm) and the michaelis-menten constant (km) in a concerned population. the aim of this study was to determine the pharmacokinetic parameters of phenytoin in a sample of iranian patients to optimize the antiepileptic pharmacotherapy. fourty patients who received a constant dose of phenytoin ...

water alternating gas (wag) technique is used in the petroleum industry to inject carbon dioxide (co2) into underground formations either for sequestration or enhanced oil recovery (eor) processes. co2 injection causes reactions with formation brine or aquifer and produces carbonic acid, the acid dissolves calcite and changes flow behavior significantly. modeling and investigating effects of co...

This paper addresses the problem of modeling maneuvering target motion in tracking applications. A target trajectory can typically be divided into segments with different dynamic motion modes, such as a constant velocity motion, a constant acceleration motion or a constant turn rate motion. To integrate the different motion modes into a uniform model, a Constant Speed Changing Rate and Constant...