PURPOSE To evaluate the safety and efficacy of an absorbable hydrogel when injected between the rectum and prostate to reduce rectal radiation toxicity in adult men undergoing Intensity Modulated Radiotherapy (IMRT) for treatment of low and intermediate risk prostate cancer. METHODS This prospective, non-randomized, multi-center, single arm, open-label study included 52 men with a confirmed d...

BACKGROUND The dose distribution to the rectum, delineated as solid organ, rectal wall and rectal surface, in 3D conformal (3D-CRT) and intensity-modulated radiotherapy treatment (IMRT) planning for localized prostate cancer was evaluated. MATERIALS AND METHODS In a retrospective planning study 3-field, 4-field and IMRT treatment plans were analyzed for ten patients with localized prostate ca...

To cite: Nwankwo N, Mirrakhimov AE, Zdunek T, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013009503 DESCRIPTION A 69-year-old man with a medical history of HIV infection and prostate cancer presented to our practice complaining of lower abdominal pain and rectal bleeding. Prostate cancer was diagnosed in 1990, for which the patient underwent radiation ...

INTRODUCTION Radiotherapy is a standard treatment for prostate cancer, and image-guided radiotherapy is increasingly being used to aid precision of dose delivery to targeted tissues. However, precision during radiotherapy cannot be maintained when unexpected intrafraction organ motion occurs. CASE PRESENTATION We report our experience of internal organ motion caused by persistent gas producti...

Introduction: Rectal cancer is a heterozygous disease in which cancerous cells grow in the rectum and lower parts of the colon. The primary cause of this cancer is not yet known, but factors such as over age 50, smoking, family history, improper diet or having a history of polyps and inflammatory bowel disease are the major risk factors for developing the rectum cancer. The rec...

PURPOSE To investigate the difference in rectal complications rate following prostate low dose rate (LDR) brachytherapy based on prostate-rectum distance and prostate longitudinal length among early prostate cancer patients. MATERIALS AND METHODS From March 2008 to February 2013, 245 prostate cancer patients with a Gleason score ≤7 were treated with 125-I LDR brachytherapy. Among them, 178 pa...

BACKGROUND The aim of the study was to evaluate toxicity after extremely hypofractionated radiotherapy (EHF-RT) using a non-isocentric robotic radiosurgery system for early stage prostate cancer. METHODS Eligibility criteria of this feasibility study were 50 - 84 years old, and low-risk to intermediate-risk disease. The prescribed dose to the iso-dose line of 95% of planning target volume was...

Introduction In UK males, prostate cancer is the most common cancer, with over 47,500 diagnosed annually. Radiotherapy a highly effective curative treatment but can be limited by dose to surrounding normal-tissues such as rectum. Radiation rectum reduced increasing distance between and hydrogel spacer. Despite National Institute of Health Care Excellence guidance, spacers are not widely funded ...

We present one of the first cases of a prostate cancer (PCa) patient with inflammatory bowel disease (IBD) treated with intensity-modulated radiotherapy (IMRT) and a hydrogel rectal spacer. A 73-year-old male with a past medical history significant for Crohn's disease (CD) and the recent diagnosis of T1cN0M0 high-risk PCa was referred for definitive radiotherapy. Given the patient's history of ...

INTRODUCTION Laparoscopy is an increasingly used approach in the surgical treatment of rectal cancer and prostate cancer. The anatomical proximity of the two organs is the main reason to consider performing both procedures simultaneously. AIM To present our first experience of laparoscopic rectal resection and radical prostatectomy, performed simultaneously, in 3 patients. MATERIAL AND METH...