OBJECTIVES To study the fetal outcome with the use of McDonald cerclage and total cervical occlusion in women with recurrent mid-trimester miscarriages or preterm deliveries, as well as complications of total cervical occlusion in the women. METHODS Prospective descriptive observational study on patients with two or more mid-trimester miscarriages, deliveries before 36 weeks, or patients who ...

Many surgical and non-surgical interventions are used in the management of threatened and recurrent miscarriages. Evidence-based management of recurrent miscarriages requires investigations into the underlying aetiology. When a specific cause is identified, directed treatment may reduce miscarriage rates. Combined aspirin and heparin for antiphospholipid syndrome, and screening and treatment of...

Background: Recurrent pregnancy loss (RPL) is a multifactorial problem associated with genetic abnormalities reflected by inherited disorders. The aim of the present study was to investigate the contribution of heterochromatin polymorphism in couples with recurrent miscarriages compared with couples without miscarriages. Materials and Methods: Over a 3 year period, we made a study of the diagno...

To the Editor: In summarizing their well-executed randomized trial, Progesterone in Recurrent Miscarriages (PROMISE), Coomarasamy et al. (Nov. 26 issue)1 state that there is no evidence of benefit from progesterone supplementation “in the first trimester” of pregnancy among women who have had three or more miscarriages. We wish to clarify three points. First, the trial did not address progester...

To study the association of chromosomal polymorphic variations with recurrent miscarriage. Recurrent miscarriage becomes a problem that affect an increasing number of couples with the frequency of about 1% in the couples who want to conceive. This study is based on comparison of chromosome Heteromorphism in the karyotypes of two groups. The first group with 400 individuals with the history of m...

Background Recurrent spontaneous abortion has been defined two or more consecutive miscarriages at 20 weeks pregnancy and one of diseases that can lead to physical, psychological and economical for the individual problems. Recently number of polymorphisms in several genes was examined for association analyses in pregnant women which related to endanger the life of the fetus. In present study we...

OBJECTIVE To assess the prevalence of uterine anatomical abnormalities found by office diagnostic hysteroscopy in a population of patients experiencing more than two consecutive miscarriages and compare the prevalence of uterine abnormalities between patients with two miscarriages and those with three or more consecutive miscarriages. METHODS A cross-sectional study of 66 patients with two or...

397 Summary Objective: To assess the prevalence of uterine anatomical abnormalities found by office diagnostic hysteroscopy in a population of patients experiencing more than two consecutive miscarriages and compare the prevalence of uterine abnormalities between patients with two miscarriages and those with three or more consecutive miscarriages. Methods: A cross-sectional study of 66 patients...

Women with mutation in both alleles of the NLRP7 or C6orf221/KHDC3L genes are predisposed to diploid biparental moles, but it has also been suggested that mutation in these genes can predispose to diploid androgenetic or triploid moles and to other kinds of reproductive wastage. We have investigated the association between molar pregnancy and recurrent miscarriages regarding changes in the NLRP...