Intraocular pressure (IOP) rise after anti-vascular endothelial growth factor (VEGF) treatment for neovascular age-related macular degeneration (AMD) can be either short-term or long-term and may require medical intervention. Short-term IOP spikes are a fairly common and well recognized complication of anti-VEGF injections. Long-term IOP rise is less well-understood and disputed as a complicati...

the aim of this study was to determine the combination effect of latanoprost and pilocarpine on theintraocular pressure and pupil size in normal rabbits. in this study, 18 rabbits were randomized to threegroups of 6 animals each. the right eyes of rabbits in group 1 were treated topically with latanoprost, ingroup 2 with pilocarpine and in group 3 with latanoprost and pilocarpine. the left eyes...

Background: In many clinical situations, knowledge of central venous pressure (CVP) is important.  Measurement of CVP is not always possible. Objective: To determine if intraocular pressure (IOP) can be used as an estimate for CVP. Methods: IOP and CVP were measured concurrently in 30 candidates of coronary artery bypass graft surgery.  Those with carotid artery or jugular venous diseases as we...

Both intraocular pressure and aqueous humour turnover rate were determined at intervals over three months in three females in order to investigate whether a correlation existed between these variables and the menstrual cycle. Not only was there a lack of correlation between intraocular pressure or aqueous humour flow rate and menses but intraocular pressure and aqueous humour flow rate were als...

purpose: to compare corneal biomechanical properties and intraocular pressure (iop) in eyes with pseudophakic bullous keratopathy (pbk) before and after descemet stripping automated endothelial keratoplasty (dsaek). methods: this prospective non-randomizedintrasubject comparative study was conducted on 44eyes of 22 patients with the diagnosis ofpbk who underwent dsaek in one eye.intraocular pre...

purpose : to evaluate the intraocular pressure (iop) rising effect of anterior versus posterior subtenon injection of triamcinolone in eyes with retinal vein occlusion methods : this prospective nonrandomized study was performed on 57 eyes of 57 patients with macular edema due to retinal vein occlusion. 26 eyes received posterior subtenon injection of 40 mg triamcinolone acetonide [pstt] and 31...

Cataract is the leading cause of blindness worldwide. Fortunately, cataract-induced blindness is reversible by cataract surgery. In addition to reclaiming lost vision, cataract surgery lowers intraocular pressure, but the reason for this remains unclear. Understanding the mechanism behind intraocular pressure reduction following cataract surgery has implication for treating glaucoma, which invo...

dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. the aim of this study is to develop ocular dorzolamide hcl nanoliposomes (drz – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. nanoliposomes were prepared using reverse-phase evaporation vesicle (rev) and thin layer hydration (tlh...

LETTERS Spontaneous venous pulsations should be monitored during glaucoma therapy It is well established that lowering intraocular pressure slows or halts progression of glau-coma. None the less, changes in intracranial pressure also affect the pressure gradient across the lamina cribrosa. Normal intraocu-lar pressures combined with low intracranial pressures produce the same pressure different...