Renomedullary interstitial cell tumor (RMICT) is a rare benign tumor of the kidney. It is usually detected incidentally at autopsies. It occurs commonly in patients above 50 years of age. This lesion is most of the times small, asymptomatic and not detected clinically. We report a case of incidental detection of this tumor at autopsy of a young female patient.

Stridh, S. 2013. Regulation of Renal Hyaluronan in Water Handling. Studies in vivo and in vitro. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 951. 76 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-8800-0. Hyaluronan (HA) is a negatively charged extracellular matrix (ECM) component with waterattracting properties. It is the dominating ECM co...

The effect of high salt intake on vascular and renomedullary prostaglandin (PG) synthesis was compared in Sprague-Dawley and salt-sensitive (S) and -resistant (R) Dahl rats. Animals were given a diet containing either 0.6% or 8% NaCl starting at 5 weeks of age, and were sacrificed 6 weeks later. Systolic blood pressure of S rats increased to 220 +/- 7 mm Hg but was unaffected in R and Sprague-D...

Partial nephrectomy-salt hypertension (PN-SH) of the rat is associated with Na volume loading. As the hypertensive state evolves, the renomedullary interstitial cells (RIC) of the renal nubbin undergo major changes, decreasing significantly in number while the remaining ones exhibit degenerative changes. The antihypertensive action of the RIC in the renal nubbin, as measured by transplants of f...

Two types of biologically active lipids have been derived from renomedullary tissue. One is neutral (ANRL) and the other polar (APRL). Upon a bolus I.V. injection, APRL causes a rapid decline of the mean arterial pressure (MAP) after a single injection and a prolonged depressor effect after either multiple injections or an infusion. APRL became evident when a reduction procedure, using the Vitr...

1. The protective action of the renal medulla was studied in one-kidney renal-clip hypertension in rats with unilateral hereditary hydronephrosis and almost complete atrophy of the medulla of the affected kidney. 2. Rats were unilaterally nephrectomized. The first group had a normal kidney remaining, and the animals from the second and third groups were left with a hydronephrotic kidney and rec...