The chronobiological effect on the pharmacokinetics of liposomal encapsulated ampicillin (LEA) was compared at noon (1200) and midnight (2400) after intravenous injection of 50 mg/kg of LEA in rats. The effects of fasting on the circadian rhythms of LEA were also investigated. Serial blood samples were collected for 2 h. Bile and urine were collected during the entire study. Plasma data was ana...

We investigate fluid transport in random velocity fields with unsteady drift. First, we propose to quantify fluid transport between flow regimes of different characteristic motion, by escape probability and mean residence time. We then develop numerical algorithms to solve for escape probability and mean residence time, which are described by backward Fokker-Planck type partial differential equ...

[ABSTRACT What does it mean to empower people through the housing in which they live, and how is this empowerment to be achieved? These are the questions which are examined in this paper. Typologies of empowerment processes are devised in an attempt to make sense of the conceptual and empirical variety involved. The distinction between ‘top-down’ and ‘bottom-up’ empowerment orientations is argu...

0009-2614/$ see front matter 2010 Elsevier B.V. A doi:10.1016/j.cplett.2010.08.019 * Fax: +972 2 651 3742. E-mail address: [email protected] The residence time of a diffusing particle in a prescribed spatial region recently finds an increasing number of applications in physics and chemistry. A partial differential equation for the residence time moments is derived, as a generalization of the ...