As with other insects, resistance to insecticides has become a limiting factor in the use of insecticides to control mosquitoes. Mosquito control depended on the use of insecticides for a long time (initially organochlorines, followed by organophosphates, carbamates and pyrethroids). This study aimed to determine the susceptibility of Anopheles arabiensis adult to the public health and agricult...

The capacity of mosquitoes to resist insecticides threatens the control of diseases such as dengue and malaria. Until alternative control tools are implemented, characterizing resistance mechanisms is crucial for managing resistance in natural populations. Insecticide biodegradation by detoxification enzymes is a common resistance mechanism; however, the genomic changes underlying this mechanis...

One of the mechanisms responsible for pyrethroid resistance in mosquitoes is mutations in domain IIS6 of voltage-gated sodium channel gene (kdr). Aedes aegypti larvae were collected from the central provinces of Thailand (Bangkok, Prachin Buri and Ratchaburi) and colonized until they became adults. Partial fragment of kdr of permethrin-resistant mosquitoes were amplified by RT-PCR and sequenced...

Mosquitoes vector many important disease pathogens. Controls of mosquito-borne diseases often involve lowering the contact rate between human and vector, and killing the vector. For instance, long lasting insecticidal nets (LLINs) act on both of these levels. Unfortunately, these are at best short-term solutions as mosquitoes are known to exhibit resistance to these interventions. Physiological...

Finding a way to block the evolution insecticide resistance would be a major breakthrough for the control of malaria. We suggest that this may be possible by introducing a stress into mosquito populations that restores the sensitivity of genetically resistant mosquitoes and that decreases their longevity when they are not exposed to insecticide. We use a mathematical model to show that, despite...

OBJECTIVES Over 20% of all malaria cases reported annually in the Republic of Korea (ROK) occur in Paju, Gyeonggi Province. Vector control for malaria management is essential, but the insecticide resistance of the vector, Anopheles mosquitoes, has been a major obstacle in implementing effective control. In this study, the insecticide resistance of the vector mosquitoes was evaluated and compare...

Malaria control is increasingly recognised as playing a key role in poverty reduction in high burdened countries. The programme for malaria eradication based on vector control using very large quantities of DDT started in 1949 in the country and resulted in a dramatic reduction in malaria incidence. Vector population recovery, mainly due to resistance to DDT in Anopheles populations as well as ...

Pyrethroid insecticides are widely used to control insect pests and human disease vectors. Voltage-gated sodium channels are the primary targets of pyrethroid insecticides. Mutations in the sodium channel have been shown to be responsible for pyrethroid resistance, known as knockdown resistance (kdr), in various insects including mosquitoes. In Aedes aegypti mosquitoes, the principal urban vect...

The evolution of insecticide resistance in mosquitoes is threatening the effectiveness and sustainability of malaria control programs in various parts of the world. Through their unique mode of action, entomopathogenic fungi provide promising alternatives to chemical control. However, potential interactions between fungal infection and insecticide resistance, such as cross-resistance, have not ...