نتایج جستجو برای: respiratory metabolism
تعداد نتایج: 425832 فیلتر نتایج به سال:
Respiratory metabolism plays an important role in energy production in the form of ATP in all aerobically growing cells. However, a limitation in respiratory capacity results in overflow metabolism, leading to the formation of byproducts, a phenomenon known as "overflow metabolism" or "the Crabtree effect." The yeast Saccharomyces cerevisiae has served as an important model organism for studyin...
Highlights • Reconstruction of mitochondrial protein import and cofactor metabolism in the model eukaryote Saccharomyces cerevisiae Quantification proton motive force shows significant energy cost metabolite transport Protein activity depends on growth rate respiratory iron-sulfur cluster requirements show dependence
The respiratory system's primary function is to provide oxygen to all the cells of the body for metabolism and to eliminate the by-product of this metabolism, carbon dioxide (Tortora and Grabowski, 2002). In this article (part three of four) we aim to explore respiratory rate and related care.
Inhaled vapors that are metabolized locally in the respiratory-tract tissues and systemically in the liver and other organs have different dose-response relationships at the portal of entry compared to systemic target organs. For instance, inhaled chloroform and styrene cause cytotoxicity in the nasal cavity at concentrations much lower that those causing hepatic or renal toxicity. Here, we dev...
In 11 normally oxygenated, normotensive mongrel dogs, blood flow and oxidative metabolism of the brain was studied during normocapnia and during respiratory alkalosis and respiratory acidosis. During respiratory alkalosis (mean PaCO2 17.8 mm Hg) CBF decreased significantly from 61.0 to 33.9 ml/100 g/min (44%) while arteriovenous-substrate differences increased and the rates of oxygen and glucos...
Mitochondrial dysfunction is associated with a spectrum of human disorders, ranging from rare, inborn errors of metabolism to common, age-associated diseases such as neurodegeneration. How these lesions give rise to diverse pathology is not well understood, partly because their proximal consequences have not been well-studied in mammalian cells. Here we provide two lines of evidence that mitoch...
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