BACKGROUND Acute retinal necrosis (ARN) syndrome is an uncommon but severe ocular disease that typically affects otherwise healthy individuals. It is frequently complicated with retinal detachment and the visual prognosis in such patients is usually poor. METHODS We operated on four eyes in four patients from 1999 through 2001. Three ophthalmologists in our hospital did these operations, resp...

In rats with primary retinal degeneration, lens extraction combined with total retinal detachment provided a model for injection of a tracer of colloidal carbon into the subretinal space. Electron microscopy and acid phosphatase cytochemistry were subsequently used to analyze the ingestion of tracer by the retinal pigment epithelium. It was found that the attachment, ingestion, and digestion ph...

The stability of the retinal chromophore attachment varies between different visual pigments and may factor in some retinal disease states. Opsin appears to stabilize this Schiff base linkage by: (i) affecting the hydrolysis chemistry, (ii) shielding the retinal linkage from solvent, or (iii) acting as a kinetic trap to slow retinal release. Here we describe methods to determine Schiff base sta...

In this report, we consider retinal detachment in the eye, which happens when the retina comes away from the choroid. This condition is often treated by removing the vitreous humour from the eye (vitrectomy) and spot-welding the retina back on to the choroid. After this, the vitreous body is refilled with saline or silicone oil. The vitreous humour is a viscoelastic material, with a very high e...

INTRODUCTION Retinal detachment remains one of the most serious complications of cataract surgery. Treatment of this condition has represented a challenge for vitreoretinal surgeons.Scleral buckle (SB) surgery is one of the treatment options in pseudophakic and aphakic retinal detachment (RD). AIMS To find out the anatomical and visual outcome of SB in pseudophakic and aphakic RD. SUBJECTS ...

PURPOSE To assess anatomic outcomes following repair of traumatic retinal detachment (RD) among a cohort of cognitively impaired adolescents with self-injurious behaviors. METHODS Main outcome measures in this retrospective, consecutive, interventional case series were retinal attachment and postoperative complications. RESULTS Complete retinal reattachment was initially achieved in all 9 e...

Cell-substratum adhesion in the embryonic chicken nervous system has been shown to be mediated in part by a 170,000-mol-wt polypeptide that is a component of adherons. Attachment of retinal cells to the 170,000-mol-wt protein is inhibited by the C1H3 monoclonal antibody and by heparan sulfate (Cole, G. J., D. Schubert, and L. Glaser, 1985, J. Cell Biol., 100:1192-1199). In the present study we ...

PURPOSE To evaluate visual and anatomical results and identify factors that influence vitrectomy and silicone oil (SO) injection outcomes in proliferative diabetic retinopathy (PDR). METHODS This retrospective study included 236 eyes with PDR that were undergoing vitrectomy and SO injection with >3-month follow-up. The primary outcomes were final best-corrected visual acuity (BCVA) and retina...

INTRODUCTION Hemorrhagic retinal macrocysts are extremely rare retinal lesions that can be mistaken for malignancy with subsequent enucleation. Such a case was diagnosed, by a retina specialist based on ultrasonography, as a choroidal melanoma with exudative retinal detachment and the patient was advised to have brachytherapy. CASE PRESENTATION A 15-year-old Caucasian boy suffered sudden visu...