The goal of this work is to predict ductile failure pipe-ring notched AISI 316L specimens, where notches mimic the geometry corrosion defects. Uncoupled damage models are used that end. Johnson-Cook and Lou-Huh criteria calibrated. uncoupled calibrated using experimental results from testing specimens. Calibration was achieved a hybrid experimental-numerical approach. Six notch shapes studied. ...

The GAGE family of tumor-associated antigens is present in a wide spectrum of human tumors but is highly restricted among normal tissues except to the testis. By reverse transcription-PCR, GAGE expression was detected in 55 of 67 neuroblastomas (NBs; 8 of 12 stage 1, 13 of 13 stage 2, 9 of 12 stage 3, 7 of 12 stage 4S, and 18 of 18 stage 4), 5 of 5 Ewing's and peripheral neuroectodermal tumors,...

The need for calibration arises frequently in the use of strain gage instrumentation. Periodic calibration is required, of course, to assure the accuracy and/or linearity of the instrument itself. More often, calibration is necessary to scale the instrument sensitivity (by adjusting gage factor or gain) in order that the registered output correspond conveniently and accurately to some predeterm...

With the advent of rapid genome sequencing, the view of the human genome as a vast desert dotted with far-flung oases of functional genes has contended with a growing appreciation of the role of regulatory sequences in shaping gene expression. The fraction of the human genome’s noncoding component that can be considered functional remains to be established, but strewn across the seeming wastela...

Perhaps the most famous brain injury in history was a penetrating wound suffered by a rail road worker named Phineas Gage on September 13, 1848. Twelve years after his injury, on the 21st of May, 1860 Phineas Gage died of an epileptic seizure. In 1868 Dr. Harlow gave an outline of Gage's case history and first disclosed his remarkable personality change. One might think this report would assure...

BACKGROUND Cancer/testis antigens (CTAs) are expressed in several cancers and during normal adult male germ cell differentiation. Little is known about their role in fetal development of human germ cells. METHODS We examined expression of the CTAs MAGE-A1, GAGE and NY-ESO-1 in fetal gonads by single and double immunohistochemical staining. RESULTS We found that GAGE was expressed in the pri...

Strain gage rosettes are used often in engineering practice to determine strain states at specific points on a structure. Figure 1 illustrates three commonly used strain gage rosette configurations. Each of these configurations is designed with a specific task in mind. The far right rosette in Figure 1 is referred to as a tee rosette. Tee rosettes are two element rosettes and should only be use...

The purpose of this project is to set up a statistical process control (SPC) system in a high volume machining center to reduce the scrap rate and improve the manufacturing quality. The system is demonstrated on a machining center at Waters Corporation as part of a team internship project. This thesis focuses on the gage repeatability and reproducibility study (Gage R&R study) for the implement...

PURPOSE Previous biomechanical studies have estimated the strains of bone and bone substitutes using strain gages. However, applying strain gages to biological samples can be difficult, and data collection is limited to a small area under the strain gage. The purpose of this study was to compare digital image correlation (DIC) strain measurements to those obtained from strain gages in order to ...

Doppler radar data are increasingly used in rainfall-runoff synthesis studies, perhaps due to radar data availability, among other factors. However, the veracity of the radar data are often a topic of concern. In this paper, three Doppler radar outcomes developed by the United States National Weather Service at three radar sites are examined and compared to actual rain gage data for two separat...