Desmoid tumours are benign monoclonal myofibroblastic neoplasms arising from musculoaponeurotic stromal tissue. They infiltrate local tissue but have no known metastatic potential. The management of desmoid tumours is complicated by their unpredictable nature and rarity, which makes study into their behaviour, and therefore treatment, a challenge. We present a case of intra-abdominal desmoid tu...

BACKGROUND Histological evidence of pervasive inflammatory infiltrate has been noted in both benign prostatic hyperplasia/hypertrophy (BPH) and prostate cancer (PCa). Cytokines known to attract particular leukocyte subsets are secreted from prostatic stroma consequent to aging and also from malignant prostate epithelium. Therefore, we hypothesized that leukocytes associated with either acute or...

Neoplastic cells are thought to have defective expression of costimulatory molecules. However, in this study, we show that human melanoma cells express LIGHT/TNFSF14, a ligand of herpesvirus entry mediator on T cells and of lymphotoxin beta receptor on stromal cells. In vitro, melanoma cells stained for LIGHT in the intracellular compartment, with weak or negative cell surface expression. Howev...

Neoplastic cells are thought to have defective expression of costimulatory molecules. However, in this study, we show that human melanoma cells express LIGHT/TNFSF14, a ligand of herpesvirus entry mediator on T cells and of lymphotoxin B receptor on stromal cells. In vitro , melanoma cells stained for LIGHT in the intracellular compartment, with weak or negative cell surface expression. However...

AIMS/BACKGROUND Adhesion molecules play a key role in the selective recruitment of different leucocyte population to inflammatory sites. The purpose of the present study was to investigate the presence and distribution of adhesion molecules in the conjunctiva of patients with vernal keratoconjunctivitis (VKC). METHODS The presence and distribution of adhesion molecules were studied in 14 conj...

PURPOSE To examine epithelial and stromal layers by three-dimensional very high-frequency (VHF) digital ultrasound scanning before and after implantation of Intacs (intracorneal ring segments [ICRS]). METHODS Three-dimensional scanning was performed in five eyes before and 3 months after Intacs insertion. Digital signal processing techniques provided high-resolution B-scan imaging and I-scan ...

Purpose Moraxella atlantae is a rare pathogen. Keratitis from this organism has never been specifically reported or described. In this report we provide the first clinical description and photograph of Moraxella atlantae infectious keratitis. Observations A 41 year-old man presented with a three day history of left eye pain. He was found to have a corneal ring ulcer and infiltrate from which ...

purpose: to assess the efficacy of polyhexamethylene biguanide (phmb) in treating acanthamoeba keratitis (ak) and also to identify related factors affecting final visual outcome in ak patients treated with phmb methods: in these interventional case series study, 27 eyes of 25 patients with ak received phmb 0.02% and divided into two groups according to the final visual acuity (va) va equal to o...

A rare case of fungal keratitis caused by Plectosporium tabacinum is reported. A 78-year-old female gardener presented with conjunctivitis and an oval infiltrate with irregular margins in the nasal half of the cornea in the right eye. Light microscopy of corneal scrapings revealed a filamentous fungus, and a diagnosis of fungal keratitis was made. The patient was admitted into our hospital on F...