Background: Human rotavirus (HRV) is the causative agent of severe gastroenteritis in children and responsible for two million hospitalizations and more than a half-million deaths annually. Sequence characteristics of the gene segments encoding the VP7 and VP4 proteins are used for the genotype classification of rotavirus. A wide variety of molecular methods are available, mainly based on rever...

background: rotavirus is one of the most common etiologic agent of severe acute diarrhea in infants and children which results in high mortality and morbidity globally. prophylactic strategies are required to prevent acute rotavirus diarrhea. recently, the beneficial effect of probiotic therapy in control of rotavirus diarrhea was noted in many investigations. this systematic review investigate...

background: the recent studies show that rotavirus is important cause of the acute gastroenteritis. the aim of this review is to estimate the number of rotavirus infection among iranian children by performing a systematic review and estimating a pooled data. methods: we performed a systematic literature review in relevant databases including pubmed, medline, ovid, sid, magiran, and iranmedex. s...

A 1:1 matched case-control study of calves under 1 month of age was carried out by weekly visits to 7 dairy farms in Mashhad from May 2008 to October 2008. Fecal samples were collected from a total of 112 calves with clinical signs of diarrhea and from 112 matched animals without clinical signs of diarrhea as assessed by a scoring system. The samples were investigated for the presence of Rotavi...

Background: Rotavirus is a major cause of acute diarrhea in children worldwide. It is an important cause of death among young children in developing countries. The aim of this study was to evaluate the prevalence of rotavirus infection in children less than five years old hospitalized for gastroenteritis in Jahrom. Methods: One hundred and two stool samples were collected from children less tha...

background human rotavirus is a significant cause of severe gastroenteritis in infants and young children worldwide. in recent years, rotavirus genotyping by rt-pcr has provided valuable information about the diversity of rotaviruses circulating worldwide. the purpose of the present study is to monitor the prevalence of the different g types of rotaviruses circulating in shiraz, southern iran a...

conclusions given the non-specific symptoms of these viruses and the high prevalence of viral diarrhea in our region, more laboratories should be equipped for virus detection and vaccination might be considered as a prevention strategy. results rotavirus was identified in 347 patients out of 827 (42%), adenovirus was detected in 76 (9%) of samples and 34 (4%) of patients had rotavirus-adenoviru...

background rotaviruses are the most common cause of viral gastroenteritis in newborns and young children. the current study intended to investigate the presence of rotavirus antigen in fecal specimens of children with acute diarrhea, to determine its prevalence and to examine its distribution pattern by age, gender and season. objectives this was a retrospective investigation of cases with rota...

Human rotavirus is a major etiologic agent for infantile diarrhea worldwide. It is responsible for up to 3.3 million deaths per year in children in developing countries. Various rapid and sensitive techniques have been developed to readily diagnose rotavirus gastroenteritis. In the present study, we compared the sensitivity and specificity of immunochromatography and RNA-polyacrylamide-gel elec...