نتایج جستجو برای: rrga
تعداد نتایج: 38 فیلتر نتایج به سال:
Streptococcus pneumoniae is the main cause of bacterial meningitis, a life-threating disease with a high case fatality rate despite treatment with antibiotics. Pneumococci cause meningitis by invading the blood and penetrating the blood-brain barrier (BBB). Using stimulated emission depletion (STED) super-resolution microscopy of brain biopsies from patients who died of pneumococcal meningitis,...
Streptococcus pneumoniae, like many other Gram-positive bacteria, assembles long filamentous pili on their surface through which they adhere to host cells. Pneumococcal pili are formed by a backbone, consisting of the repetition of the major component RrgB, and two accessory proteins (RrgA and RrgC). Here we reconstruct by transmission electron microscopy and single particle image reconstructio...
The pilus is an extracellular structural part that can be detected in some Streptococcus pneumoniae ( S. ) isolates (type I pili are found approximately 30% of strains, while type II 20%). It anchored to the cell wall by LPXTG-like motifs on peptidoglycan. Two kinds have been discovered, namely, pilus-1 and pilus-2. former encoded islet 1 (PI-1) a polymer formed protein subunits RrgA, RrgB RrgC...
The proper temporal expression of virulence genes during infection is crucial to the infectious life cycle of microbial pathogens, particularly in pathogens that encounter a multitude of environments in eukaryotic hosts. Streptococcus pneumoniae normally colonizes the nasopharynges of healthy adults but can cause a range of diseases at a variety of host sites. Transcriptional regulators that ar...
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