نتایج جستجو برای: rs2292832

تعداد نتایج: 50  

2016
Xinhang Jiang Xintong Chen Linhua Liu Huanwen Tang

Gastric cancer is the second most frequent cause of cancer-related deaths worldwide. MicroRNAs (miRNAs) are a novel class of endogenous noncoding regulatory sequences that interact with tumor oncogenes and suppressors. Many studies have indicated that single-nucleotide polymorphisms (SNPs) in miRNAs influence the susceptibility of gastric cancer. MiRNA SNPs have been explored for several years ...

Journal: :iranian journal of basic medical sciences 0
jia-yuan pu department of respiratory, the first hospital, lanzhou university, lanzhou 730000, china wei dong department of immunology, west china school of preclinical and forensic medicine, sichuan university, chengdu 610041, china lin zhang department of forensic biology, west china school of preclinical and forensic medicine, sichuan university, chengdu 610041, china wei-bo liang department of forensic biology, west china school of preclinical and forensic medicine, sichuan university, chengdu 610041, china yan yang department of obstetrics and gynecology, west china second university hospital, sichuan university, chengdu 610041, china mei-li lv department of immunology, west china school of preclinical and forensic medicine, sichuan university, chengdu 610041, china

objective(s): accumulating evidence has demonstrated that mirnas contribute to various genetic and epigenetic modifications in the pathogenesis of gastric cancer (gc). recent studies focused on the four single nucleotide polymorphisms (snps) of pre-mirnas including rs11614913, rs3746444, rs2910164, and rs2292832. it was suggested that these four snps were significantly associated with the risk ...

2016
Jae Joon Lim Dong Ah Shin Young Joo Jeon Hemant Kumar Seil Sohn Hyoung Sik Min Jang Bo Lee Sung Uk Kuh Keung Nyun Kim Jung Oh Kim Ok Joon Kim Alexander E. Ropper Nam Keun Kim In Bo Han

BACKGROUND Ossification of the posterior longitudinal ligament (OPLL) of the spine is considered a multifactorial and polygenic disease. We aimed to investigate the association between four single nucleotide polymorphisms (SNPs) of pre-miRNAs [miR-146aC>G (rs2910164), miR-149T>C (rs2292832), miR-196a2T>C (rs11614913), and miR-499A>G (rs3746444)] and the risk of cervical OPLL in the Korean popul...

2014
Ye Hu Chen-Yang Yu Ji-Lin Wang Jian Guan Hao-Yan Chen Jing-Yuan Fang

MicroRNAs (miRNAs) participate in diverse biological pathways and may act as oncogenes or tumor suppressors. Single nucleotide polymorphisms (SNPs) in miRNAs (MirSNPs) might promote carcinogenesis by affecting miRNA function and/or maturation; however, the association between MirSNPs reported and cancer risk remain inconsistent. Here, we investigated the association between nine common MirSNPs ...

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