Protein Z-dependent protease inhibitor (ZPI) is a 72 kDa single-chain serpin which inhibits the activated coagulation factors X and XI. Two non-sense polymorphisms of ZPI, R67X and W303X, were recently identified, and were linked with a prothrombotic state. Here, we investigated the association of the R67X (728C>T) and W303X (1438G>A) variants in the ZPI gene with recurrent spontaneous miscarri...

The aim of the present study was to examine the reliability of a novel multi-direction repeated sprint ability (RSA) test [RSM; 10 × (6 × 5-m)] compared with a RSA with one change of direction [10 × (2 × 15-m)], and the relationship of the RSM and RSA with Yo-Yo intermittent recovery test level 1 (Yo-Yo IR1) and jump performances [squat jump (SJ) and counter-movement-jump (CMJ)]. Thirty-six (ma...

The present study aimed to develop the predictive models of average tool-workpiece interface temperature in hard turning of AISI 1060 steels by coated carbide insert. The Response Surface Methodology (RSM) and Artificial Neural Network (ANN) were employed to predict the temperature in respect of cutting speed, feed rate and material hardness. The number and orientation of the experimental trial...

The Seoul Road Sign Management (RSM) is a system which provides the semantic integration of LOD’s Linked Geo Data and Open Street Map with Korean POI data set. That is an attempt to develop intelligent road sign management system based on the LarKC platform. The RSM data set contains over 1.1 billion triples of semantic data. However, significant amount of the RSM data are noisy (e.g., inconsis...

Rotating Sbox Masking (RSM) scheme is a lightweight and highly efficient first-order masking scheme proposed to protect cryptographic implementations like AES from side channel attacks. It is a Low Entropy Masking Scheme (LEMS) and has attracted special attention from academia and industry with its low overhead and high performance. The two public targets of DPA Contest v4 are both RSM-masked A...

This trial was performed to study the effects of replacing soybean meal (SBM) with fermented rapeseed meal (RSM) on growth performance, serum biochemistry variable and intestinal morphology of broilers. A total of 640 d-old Arbor Acres broiler chicks were randomly allocated to 4 dietary treatments, 4 pens per treatment and 40 birds per pen for a 6-wk feeding trial. In the four treatment groups,...

Gallic acid is a major phenolic pollutant present in the wastewater generated from cork boiling, olive mill, and pharmaceutical industries. Experimental and statistical modelling using response surface methodology (RSM) and artificial neural network (ANN) were carried out for reactive separation of gallic acid from aqueous stream using tri-nbutyl phosphate (TBP) in hexanol. TBP has a more signi...

From the historical point of view, the article by Box and Wilson [1] is considered to be the first for having laid the foundations for RSM. Some of the early papers that also contributed to the development of RSM include those by Box and Hunter [2] and Box and Draper [3]. Several review papers on RSM were subsequently published starting with the article by Hill and Hunter [4] that emphasized pr...

Thermal damage to proteins can reduce their nutritional value. The effects of toasting time on the kinetics of hydrolysis, the resulting molecular weight distribution of 00-rapeseed meal (RSM) and the soluble and insoluble protein fractions separated from the RSM were studied. Hydrolysis was performed with pancreatic proteases to represent in vitro protein digestibility. Increasing the toasting...

Response surface methods (RSM) provide superb statistical tools for design and analysis of experiments aimed at process optimization. At the final stages of process development, RSM illuminates the sweet spot where high yield of in-specification products can be achieved at lowest possible cost. It produces statistically-validated predictive models and, with the aid of specialized software, resp...