Bed rest is a recognized model for muscle atrophy and bone loss in space flight and in clinical medicine. We hypothesized that whole body vibration in combination with resistive exercise (RVE) would be an effective countermeasure. Twenty healthy male volunteers underwent horizontal bed rest for 56 days and were randomly assigned either to a group that performed RVE 11 times per week or to a gro...

Preservation of muscle function, known to decline in microgravity and simulation (bed rest), is important for successful spaceflight missions. Hence, there is great interest in developing interventions to prevent muscle-function loss. In this study, 20 males underwent 56 days of bed rest. Ten volunteers were randomized to do resistive vibration exercise (RVE). The other 10 served as controls. R...

behaviour. W chemical ch not known, the neurona providing ev of aspects o 1991; Paul, needed, however, because although circuits and their components do change, it is not yet clear which features are relatively well conserved and which are modified. One difficulty of using the comparative method in an evolutionary context is deriving an acceptable representation of the primitive condition by ev...

Abstraet. Composite material elastic behavior has been studied using many approaches, all of which are based on the concept of a Representative Volume Element (RVE). Most methods accurately estimate effective elastic properties when the ratio of the RVE size to the global structural dimensions, denoted here as ~/, goes to zero. However, many composites are loeally periodic with finite q. The pu...

We present a Finite Element (FE) approach to model the conductivity and strain-sensing capabilities of Carbon Nanotube (CNT) reinforced polymer composites. A periodic Representative Volume Element (RVE) is constructed based on measurable statistical descriptors of the microstructure, and its response is simulated by concurrent electrical and mechanical FE analyses; the scatter of the prediction...

Fat accumulates in the bone marrow of lumbar vertebrae with bed rest. Exercise with or without whole body vibration may counter this effect. Our objectives were to measure 1) the vertebral fat fraction (VFF) of men subjected to bed rest who performed resistive exercises with (RVE, n = 7) or without whole body vibration(RE, n = 8) or no exercise (CTR, n = 9) using three MRI techniques; and 2) ch...

Spaceflight and bed rest (BR) result in loss of muscle mass and strength. This study evaluated the effectiveness of resistance training and vibration-augmented resistance training to preserve thigh (quadriceps femoris) and calf (triceps surae) muscle cross-sectional area (CSA), isometric maximal voluntary contraction (MVC), isometric contractile speed, and neural activation (electromyogram) dur...

Engineering structures must be designed for an extremely low failure probability, Pf < 10 6. To determine the corresponding structural strength, a mechanics-based probability distribution model is required. Recent studies have shown that quasibrittle structures that fail at the macrocrack initiation from a single representative volume element (RVE) can be statistically modeled as a finite chain...

This study focused on the contribution of micromechanical parameters on the macro-mechanical response of short fiber composites, namely polypropylene matrix reinforced by glass fibers. In the framework of this paper, an attention has been given to the glass fibers length, as micromechanical parameter influences the overall macroscopic material’s behavior. Three dimensional numerical models were...