نتایج جستجو برای: rvfv

تعداد نتایج: 294  

Journal: :Journal of virology 2017
Ashwini Brahms Rajini Mudhasani Chelsea Pinkham Krishna Kota Farooq Nasar Rouzbeh Zamani Sina Bavari Kylene Kehn-Hall

There is an urgent need for therapeutic development to combat infections caused by Rift Valley fever virus (RVFV), which causes devastating disease in both humans and animals. In an effort to repurpose drugs for RVFV treatment, our previous studies screened a library of FDA-approved drugs. The most promising candidate identified was the hepatocellular and renal cell carcinoma drug sorafenib. Me...

2014
Matthieu Roger Marina Beral Séverine Licciardi Miradje Soulé Abdourahime Faharoudine Coralie Foray Marie-Marie Olive Marianne Maquart Abdouroihamane Soulaimane Ahmed Madi Kassim Catherine Cêtre-Sossah Eric Cardinale

Rift Valley fever virus (RVFV) is an arthropod-borne phlebovirus reported to be circulating in most parts of Africa. Since 2009, RVFV has been suspected of continuously circulating in the Union of Comoros. To estimate the incidence of RVFV antibody acquisition in the Comorian ruminant population, 191 young goats and cattle were selected in six distinct zones and sampled periodically from April ...

Journal: :Transboundary and emerging diseases 2015
B R Beechler R Bengis R Swanepoel J T Paweska A Kemp P Jansen van Vuren J Joubert V O Ezenwa A E Jolles

Rift Valley fever (RVF) is a zoonotic mosquito-borne virus disease of livestock and wild ruminants that has been identified as a risk for international spread. Typically, the disease occurs in geographically limited outbreaks associated with high rainfall events and can cause massive losses of livestock. It is unclear how RVF virus persists during inter-epidemic periods but cryptic cycling of t...

2018
Renée Zakhia Laurence Mousson Marie Vazeille Nabil Haddad Anna-Bella Failloux

West Nile virus (WNV) and Rift Valley fever virus (RVFV) are two emerging arboviruses transmitted by Culex pipiens species that includes two biotypes: pipiens and molestus. In Lebanon, human cases caused by WNV and RVFV have never been reported. However, the introduction of these viruses in the country is likely to occur through the migratory birds and animal trades. In this study, we evaluated...

2003
B. NIKLASSON C. J. PETERS M. GRANDIEN O. WOOD

Rift Valley fever virus (RVFV) is an important human and animal pathogen in Africa and has been responsible for infections in travelers. Because of the aerosol infectivity and risk of dissemination of the virus, a need exists for simple, safe, serological tests for diagnosis. An enzyme-linked immunosorbent assay (ELISA) was developed to detect RVFV-specific immunoglobulin (immunoglobulin G [IgG...

Journal: :The Onderstepoort journal of veterinary research 1999
M J Oelofsen E Van der Ryst

The inter-epizootic reservoir host of Rift Valley fever virus (RVFV) remains unknown, although the namaqua rock rat, Aethomys namaquensis, as well as bats have been implicated. Bats can be asymptomatically infected with rabies, as well as several arboviruses; the possibility that they can act as host for RVFV therefore exists. To examine this possibility, 350 different samples (brain, liver, sa...

2017
Tetsuro Ikegami Aaron Balogh Shoko Nishiyama Nandadeva Lokugamage Tais B Saito John C Morrill Vinay Shivanna Sabarish V Indran Lihong Zhang Jennifer K Smith David Perez Terry L Juelich Igor Morozov William C Wilson Alexander N Freiberg Juergen A Richt

Rift Valley fever phlebovirus (RVFV) causes high rates of abortions and fetal malformations in ruminants, and hemorrhagic fever, encephalitis, or blindness in humans. Viral transmission occurs via mosquito vectors in endemic areas, which necessitates regular vaccination of susceptible livestock animals to prevent the RVF outbreaks. Although ZH501 strain has been used as a challenge strain for p...

2013
Nazly Shafagati Aarthi Narayanan Alan Baer Katherine Fite Chelsea Pinkham Charles Bailey Fatah Kashanchi Benjamin Lepene Kylene Kehn-Hall

BACKGROUND Rift Valley Fever Virus (RVFV) is a zoonotic virus that is not only an emerging pathogen but is also considered a biodefense pathogen due to the threat it may cause to public health and national security. The current state of diagnosis has led to misdiagnosis early on in infection. Here we describe the use of a novel sample preparation technology, NanoTrap particles, to enhance the d...

2017
Isabelle Dietrich Stephanie Jansen Gamou Fall Stephan Lorenzen Martin Rudolf Katrin Huber Anna Heitmann Sabine Schicht El Hadji Ndiaye Mick Watson Ilaria Castelli Benjamin Brennan Richard M Elliott Mawlouth Diallo Amadou A Sall Anna-Bella Failloux Esther Schnettler Alain Kohl Stefanie C Becker

The emerging bunyavirus Rift Valley fever virus (RVFV) is transmitted to humans and livestock by a large number of mosquito species. RNA interference (RNAi) has been characterized as an important innate immune defense mechanism used by mosquitoes to limit replication of positive-sense RNA flaviviruses and togaviruses; however, little is known about its role against negative-strand RNA viruses s...

2012
Fadila Amraoui Ghazi Krida Ali Bouattour Adel Rhim Jabeur Daaboub Zoubir Harrat Said-Chawki Boubidi Mhamed Tijane Mhammed Sarih Anna-Bella Failloux

West Nile fever (WNF) and Rift Valley fever (RVF) are emerging diseases causing epidemics outside their natural range of distribution. West Nile virus (WNV) circulates widely and harmlessly in the old world among birds as amplifying hosts, and horses and humans as accidental dead-end hosts. Rift Valley fever virus (RVFV) re-emerges periodically in Africa causing massive outbreaks. In the Maghre...

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