نتایج جستجو برای: safety threshold
تعداد نتایج: 382282 فیلتر نتایج به سال:
Purpose Although activated protein C (APC) is effective in preventing the death of retinal neurons in ischemic retinopathy, it is not known at what concentrations it becomes retinotoxic. The purpose of this study was to determine the concentrations of intravitreal APC that are safe and those that are toxic for the retina, using rabbit eyes. Methods The left eyes of 12 rabbits received an intrav...
Pulse oximeters have become essential devices for evaluating and monitoring patient oxygenation. The probe emits a small amount of heat into the skin in the process of signal detection. Regulations set by the Food and Drug Administration currently limit the maximum allowable temperature of an oximeter probe to 41 degrees C. As a result of the prolonged exposure of extremities to these devices, ...
Safety critical systems or applications must satisfy safety requirements ensuring that catastrophic consequences of combined component failures are avoided or kept below a satisfying probability threshold. Therefore, designers must define a hardened architecture (or implementation) of each application, which fulfills the required level of safety by integrating redundancy and safety mechanisms. ...
In 2006, the Product Quality Research Institute’s (PQRI) Leachables and Extractables Working Group released a comprehensive and detailed recommendation document related to leachables and extractables for inhalation drug products. The document includes best pharmaceutical development practice recommendations regarding container closure/delivery system component composition and selection, control...
Ventricular capture management is an automatic pacing threshold adjustment algorithm that automatically measures pacing threshold through detection of the evoked response after a pacing stimulus. Although it is principally designed to save device battery under the maintenance of the patient׳s safety, we experienced a rare case with serious pacing failure due to a weakness of this algorithm. Thi...
FUNCTION Mass/energy flow and balance GENERAL FUNCTION Flow and storage of heat, etc. PHYSICAL FUNCTION States of components what? what? what? what? what?
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