Objective: Tyrosinase as the key enzyme in melanin biosynthesis, involves in determining the color of mammalian skin and hair. A variety of dermatological disorders, come up from an unnecessary level of epidermal pigmentation. Plants are low-cost and rich sources of active compounds.  Methods: More than seventy native plants collected from the central region of Kurdistan province collected. Inh...

objective: tyrosinase as the key enzyme in melanin biosynthesis, involves in determining the color of mammalian skin and hair. a variety of dermatological disorders, come up from an unnecessary level of epidermal pigmentation. plants are low-cost and rich sources of active compounds.  methods: more than seventy native plants collected from the central region of kurdistan province collected. inh...

background and objectives: alzheimer's disease (ad) as a neurodegenerative disorder is the most common form of dementia in the elderly. according to the amyloid hypothesis, accumulation of amyloid beta (aβ) plaques, which are mostly constituted of aβ peptide aggregates, triggers pathological cascades that lead to neuronal cell death. thus, modulation of aβ toxicity is the hopeful therapeut...

range forage of vicia variabilis, astragalus spp., medicago sativa, prangos uloptera and sanguisorba minor was sampled during three phenological stages from the controlled rangeland stations in chaharmahal and bakhtiari province, iran. samples were analyzed for the determination of crude protein (cp%), ether extract (ee), crude fiber (cf), total ash, neutral detergent fiber (ndf), acid detergen...

Essential oil, ethanolic extract and decoction of 10 plant species from interior Portugal were analyzed for their activity towards acetylcholinesterase (AChE) enzyme and their antioxidant activity. Of these, Melissa officinalis, Paronychia argentea, Sanguisorba minor, Hypericum undulatum and Malva silvestris are used in herbal medicine, Laurus nobilis and Mentha suaveolens as condiments, and Sa...

The current study, devoted to leaf micromorphology of tribe Agrimonieae in Iran including three genera (Agrimonia, Aremonia,and Sanguisorba),four species (Agrimonia eupatoria,Aremonia agrimonioides,S. minor, and S. officinalis), and six subspecies (A. eupatoria subsp. eupatoria, A. eupatoria subsp. grandis, A. eupatoria subsp. asiatica, S. minor subsp. minor, S. minor subsp. lasiocarpa, and S. ...

Overexpression of suprachiasmatic nucleus circadian oscillatory protein (SCOP), a negative ERK regulator, blocks long-term memory encoding. Inhibition of calpain-mediated SCOP degradation also prevents the formation of long-term memory, suggesting rapid SCOP breakdown is necessary for memory encoding. However, whether SCOP levels also control the magnitude of long-term synaptic plasticity is un...