نتایج جستجو برای: sapovirus
تعداد نتایج: 291 فیلتر نتایج به سال:
Functional characterization of the cleavage specificity of the sapovirus chymotrypsin-like protease.
Sapovirus is a positive-stranded RNA virus with a translational strategy based on processing of a polyprotein precursor by a chymotrypsin-like protease. So far, the molecular mechanisms regulating cleavage specificity of the viral protease are poorly understood. In this study, the catalytic activities and substrate specificities of the predicted forms of the viral protease, the 3C-like protease...
Sapovirus, a member of the Caliciviridae family, is an important cause of acute gastroenteritis in humans and pigs. Currently, the porcine sapovirus (PSaV) Cowden strain remains the only cultivable member of the Sapovirus genus. While some caliciviruses are known to utilize carbohydrate receptors for entry and infection, a functional receptor for sapovirus is unknown. To characterize the functi...
We report here the first near-complete genome sequence (7,463 nucleotides) of a human sapovirus GI.2 variant from Dublin, Ireland, detected in an adult with gastroenteritis in 2016.
closely related to E. coli, as was previously observed in Tanzania (9). This finding is also the first report of CTXM-3 in sub-Saharan Africa. Multidrug resistance profiles involving non–β-lactam antimicrobial drugs coselected these ESBL-producing isolates. We suggest that the misuse of antimicrobial drugs in the Central African Republic and the migratory flux of regional populations could resu...
Sapoviruses are etiologic agents of human gastroenteritis. We detected sapovirus in untreated wastewater, treated wastewater, and a river in Japan. A total of 7 of 69 water samples were positive by reverse transcription-PCR. Phylogenetic analysis of the viral capsid gene grouped these strains into 4 genetic clusters.
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