نتایج جستجو برای: sar structureactivity relationship

تعداد نتایج: 569880  

2016
Xubin Pan Xiuling Zhang Feng Wang Shuifang Zhu

The Species-Area Relationship (SAR) has been widely employed to assess species diversity and predict species extinction. Thus far, although many functions were proposed to fit SAR based on field observations or simulation results, the shape of SAR curve has been debated extensively over decades. Here we uncover a potential global-local inconsistency in SARs fitting simulation blocked by the lim...

2013
Xubin Pan

Species-area theory is an important concept in ecology. However, debates still surround the species-area relationship (SAR) or endemics-area relationship (EAR) and their relations to expected extinction rates. In this paper, I introduce the concept of overlap-area relationship (OAR) to link SAR and EAR. Two fundamental equations are derived from the relationship between the area and species num...

Journal: :The Journal of antibiotics 1995
T Shibata S Kurihara T Oikawa N Ohkawa N Shimazaki K Sasagawa T Kobayashi T Kohama F Asai A Shiraishi

enzymatically prepared by removing acyl moieties from the cyclohexane ring of LSNs, and its thrombopoietic effects. Furthermorewealso report on the structureactivity relationship of its derivatives. A mixture of LSNswas treated with porcine liver esterase (PLE-A) in acetone-phosphate buffer (pH = 6.7) at 37°C, after filtering off the enzyme, purification by Cosmosil column afforded LSN-H (Id) a...

2013
PRASHANTHA KARUNAKAR

The structure of 2,3-Bis-(1-furan-2-yl-ethylidene)-succinic acid (Furan succinic acid (FSA)) has been established by X-ray crystallography to understand the structureactivity relationship, which is of paramount importance in the pharmaceutical studies of the compound. Compound showed carbonyl–π and C—H...O interactions along with O-H...O interactions in the assembly of the supramolecular archit...

2009
Gene M. Ko A. Srinivas Reddy Sunil Kumar Rajni Garg Srinivas Reddy

A data mining study has been done using HIV-1 protease crystal structures complexed with FDA approved HIV-1 protease inhibitor drugs. Chemical descriptors have been computed for the binding pockets of each crystal structure, yielding approximately 600 constitutional, topological, geometric, elecrotostatic, and quantum mechanical descriptors for each structure. Several supervised (hybrid binary ...

2012
Hone-Jay Chu

A spatially autocorrelated effect exists in precipitation of a mountainous basin. This study examines the relationship between maximum annual rainfall and elevation in the Kaoping River Basin of southern Taiwan using spatial regression models (i.e. geographically weighted regression (GWR), simultaneous autoregression (SAR), and conditional autoregression (CAR)). Results show that the GWR, SAR, ...

2016
Guojun Hu Li Zhang Gang Li Hui Gong Jinchun Qin

SAR interferometry with distributed satellites is a technique based on the exploitation of the interference pattern of two SAR images acquired synchronously. The interferogram contains geometric, atmospheric, topographic and land defomation. This paper focuses on atmospheric effects on SAR interferometry, which shows theoretically that the relationship among ionosphere TEC and troposphere param...

2002
D. L. SUAREZ

The relation between the sodium adsorption ratio (SAR) and pHc derived here predicts SAR of the drainage water (SARdw) better than existing empirical equations. Inaccuracies in SAR estimates from the new relationship can be anticipated by the extent to which the derived conditions are valid. Empirical equations provide no understanding of why they are sometimes inaccurate. Due to the relative i...

2010
Xia Ning

In this article, we review the recent development for in silico Structure-Activity-Relationship (SAR) models using machine-learning techniques. The review focuses on the following topics: machine-learning algorithms for computational SAR models, single-target-oriented SAR methodologies, Chemogenomics, and future trends. We try to provide the state-of-the-art SAR methods as well as the most up-t...

2006
Yosio E. Shimabukuro Ramon M. de Freitas

This paper presents a comparison between L-band HH JERS-1 SAR and Landsat TM data for land cover assessment in an Amazonian test site. For this, a study area located in the south of Rondônia State, western Brazilian Amazonia, was selected. The Landsat TM data acquired on August 1 1997 were converted to vegetation, soil, and shade fraction images, using a Linear Spectral Mixing Model. These frac...

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