AIMS primary pancreatic sarcomas represent an extremely rare histopathological entity accounting for less than 0.1% of all pancreatic malignancies. Pancreatic sarcomas tend to be more aggressive and have a poor prognosis. METHODS the case of a 52 year old patient presenting with jaundice is presented and the available literature was reviewed. RESULTS primary pancreatic sarcomas are extremel...

Soft-tissue sarcomas are relatively rare with approximately 8,600 new cases annually and represent less than 1% of all n ew l y d i agnosed ma l i gnanc i e s . Retroperitoneal sarcomas are malignant tumours arising from mesenchymal cells, which are usually located in muscle, fat, and connective tissues. One-third of malignant tumours located in the retroperitoneum are sarcomas, and approximate...

Sarcomas are malignant tumors of mesenchymal origin. They comprise < 1% adult malignancies and about 15-20% pediatric malignancies. These subdivided into bone cartilage sarcomas soft tissue type. the maxillofacial region 5-10% all this part body. Usually do not originate from benign tumors. Among factors known to induce sarcoma growth are: genetic defects, exposure pesticides herbicides, ionizi...

Whereas most solid tumors are characterized by considerable genetic instability and molecular heterogeneity, sarcomas include many subtypes with very specific underlying molecular events driving oncogenesis. Gene expression profiling and other modern techniques have consequently had particular success in identifying the critical biologic pathways active in specific sarcomas, yielding insights w...

Uterine sarcomas are a rare group of neoplasms with aggressive clinical course and poor prognosis. They are classified into four main histological subtypes in order of decreasing incidence: carcinosarcomas, leiomyosarcomas, endometrial stromal sarcomas and "other" sarcomas. The pathological subtype demands a tailored approach. Surgical resection is regarded as the mainstay of treatment. Total a...

Mesenchymal stem cells (MSCs) are believed to be the cell of origin for most sarcomas including osteosarcoma and malignant fibrous histiocytoma (MFH/UPS). To identify the signaling pathways involved in sarcoma pathogenesis, we compared gene expression profiles in rat osteosarcoma and MFH cells with those in syngeneic rat MSCs. Analysis of genes that characterize MSCs such as CD44, CD105, CD73, ...

Intraluminal formations of the heart are a heterogeneous group: from blood clots to malignant neoplasms. The nosology these can only be determined by morphological research. Myxofibrosarcoma is rare tumor. According modern concepts, myxofibrosarcoma belongs group intimal sarcomas, subgroup undifferentiated pleomorphic sarcomas. We describe two cases heart: in one subject against background infl...