UNLABELLED Cardiac SPECT images are degraded by photons scattered in the thorax. Accurate correction for scatter is complicated by the nonuniform density and varied sizes of thoraxes and by the additional attenuation and scatter caused by female patients' breasts. Monte Carlo simulation is a general and accurate method for detailed modeling of scatter. Hence, for 99mTc we compared statistical r...

UNLABELLED Planar gamma-scintigraphy is often used to quantify pulmonary deposition patterns from aerosol inhalers. The results are quite different from those obtained using 3-dimensional PET and SPECT. The purpose of this study was to characterize the effects of scatter and tissue attenuation on the distribution of radiolabeled aerosol as measured by planar scintigraphy using Monte Carlo simul...

Planar g-scintigraphy is often used to quantify pulmonary deposition patterns from aerosol inhalers. The results are quite different from those obtained using 3-dimensional PET and SPECT. The purpose of this study was to characterize the effects of scatter and tissue attenuation on the distribution of radiolabeled aerosol as measured by planar scintigraphy using Monte Carlo simulations. This st...

BACKGROUND Soft tissue attenuation is a prominent cause of single-photon emission computed tomography (SPECT) imaging artifacts, which may result in reduced diagnostic accuracy of myocardial perfusion imaging. A method incorporating simultaneously acquired transmission data permits nonuniform attenuation correction and when incorporating scatter correction and resolution compensation may substa...

PURPOSE An attenuation correction is necessary to improve quantitative SPECT evaluation. The aim of this study was to evaluate the performance of several different types of commercial attenuation correction algorithms. METHODS We investigated the performance of four attenuation correction algorithms using a simulation phantom with and without scatter. The attenuation correction was performed ...

UNLABELLED We determined the relative effect of corrections for scatter, depth-dependent collimator response, attenuation, and finite spatial resolution on various image characteristics in cardiac SPECT. METHODS Monte Carlo simulations and real acquisition of a 99mTc cardiac phantom were performed under comparable conditions. Simulated and acquired data were reconstructed using several correc...

In the flat panel detector-based cone beam CT system, the scatter photons which reach the flat panel detector increase the detected signal, produce the image cupping artifact and reduce the image contrast. To conquer the X-Ray scatter problem, this study proposes the beam attenuation grid -based scatter correction algorithm that needs to add a beam attenuation grid (BAG) between the X-Ray sourc...

We describe an ordinary Poisson list-mode expectation maximization (OP-LMEM) algorithm with a sinogram-based scatter correction method based on the single scatter simulation (SSS) technique and a random correction method based on the variance-reduced delayed-coincidence technique. We also describe a practical approximate scatter and random-estimation approach for dynamic PET studies based on a ...

In positron emission tomography (PET), photon scattering inside the body causes significant blurring and quantification error in the reconstructed images. To solve this problem we have developed Monte Carlo (MC) based 3D PET reconstruction algorithms implemented on the Graphics Processing Unit (GPU). Our implementation takes multiple Compton scattering into account without any significant addit...

Soft tissue images from portable cone beam computed tomography (CBCT) scanners can be used for diagnosis and detection of tumor, cancer, intracerebral hemorrhage, and so forth. Due to large field of view, X-ray scattering which is the main cause of artifacts degrades image quality, such as cupping artifacts, CT number inaccuracy, and low contrast, especially on soft tissue images. In this work,...