1 This work is supported by the National Natural Science Foundation of China under grand 60472069 Summary In this paper a novel distortion-tolerant fingerprint registration method based on centroid structure vector (CSV) and Vector Line Segment (VLS), is proposed. In this method, minutia features of the query fingerprint are clustered into various clusters and a set of VLS is extracted. Several...

Virtual library screening (VLS) is emerging as a valuable drug lead discovery tool. ICM-VLS implementation of this technology was evaluated on a benchmark set of nuclear hormone receptors (NRs), an important therapeutic target family. Over 5000 structurally diverse compounds, including 78 known NR ligands, were screened against 18 crystal structures and one computer model of 10 NR ligand bindin...

BACKGROUND Substantial evidence gaps remain regarding human immunodeficiency virus (HIV) intervention strategies that improve engagement in care (EiC) and viral load suppression (VLS). We assessed EiC and VLS before and after enrollment in a comprehensive intervention for persons at risk of poor HIV care outcomes. METHODS New York City's Ryan White Part A HIV Care Coordination Program (CCP), ...

A method for growth of ultralarge grain (>100 μm) semiconductor thin-films on nonepitaxial substrates was developed via the thin-film vapor−liquid−solid growth mode. The resulting polycrystalline films exhibit similar optoelectronic quality as their single-crystal counterparts. Here, deterministic control of nucleation sites is presented by substrate engineering, enabling user-tuned internuclei...

Nanowires make possible to manipulate light in novel methods and thus are promising materials for advanced optoelectronics. To exploit the potential, the growth behavior has to be controlled since it dominates the physical and chemical states and, in turn, the optical properties of nanowires. In this chapter, the vapor–liquid–solid (VLS) mechanism for the growth and modulation of nanowires was ...

Knowledge of the catalyst concentration within vapor-liquid-solid (VLS) grown semiconductor wires is needed in order to assess potential limits to electrical and optical device performance imposed by the VLS growth mechanism. We report herein the use of secondary ion mass spectrometry to characterize the Au catalyst concentration within individual, VLS-grown, Si wires. For Si wires grown by che...

Virtual learning system (VLS) is an information system that facilitates e-learning have been widely implemented by higher education institutions to support face-to-face teaching and self-managed learning in the virtual learning and education environment (VLE). This is referred to a blended learning instruction. By adopting the VLS, students are expected to enhance learning by getting access to ...

Efficient acquisition and transmission of Borrelia burgdorferi by the tick vector, and the ability to persistently infect both vector and host, are important elements for the life cycle of the Lyme disease pathogen. Previous work has provided strong evidence implicating the significance of the vls locus for B. burgdorferi persistence. However, studies involving vls mutant clones have thus far o...

BACKGROUND The human T lymphotropic virus (HTLV)-I or -II proviral load (VL) may be linked to viral pathogenesis, but prospective data on VL and disease outcomes are lacking. METHODS Using data from a prospective cohort study of HTLV disease outcomes, we examined baseline VLs with real-time quantitative polymerase chain reaction in 122 HTLV-I- and 319 HTLV-II-infected subjects and serial VLs ...

We set out to gain deeper insight into the potential of antibody light chain variable domains (VLs) as immunotherapeutics. To this end, we generated a naïve human VL phage display library and, by using a method previously shown to select for non-aggregating antibody heavy chain variable domains (VHs), we isolated a diversity of VL domains by panning the library against B cell super-antigen prot...