The sclera is the tough outer covering of the eye that provides structural support and helps maintain intraocular pressure. In some fishes, reptiles, and birds, the sclera is reinforced with an additional ring of hyaline cartilage or bone that forms from scleral ossicles. Currently, the evolutionary and genetic basis of scleral ossification is poorly understood, especially in teleost fishes. We...

By Gaurav K. Shah, MD; and Baseer Ahmad, MD Is scleral buckling surgery for retinal detachment (RD) repair here to stay? We believe the answer is “yes,” but only if ophthalmologists continue to perform and teach these procedures. If we do not, scleral buckling procedures will pass into history. There is no doubt that pars plana vitrectomy (PPV) is an effective procedure, valued day in and day o...

BACKGROUND/AIMS Macular translocation with scleral imbrication is a new technique for treating subfoveal choroidal neovascular membranes (CNV). This procedure shortens the sclera but may result in a minimal decrease in the internal circumference of the globe and limits the amount of foveal displacement. The authors propose a new scleral retraction suture aimed at decreasing the internal circumf...

PURPOSE The authors report a case of fungal scleral keratitis and endophthalmitis as a complication of pterygium surgery. METHODS Case presentation. RESULTS A 46-year old woman underwent pterygium excision with topical use of intraoperative mitomycin C. By day 21 after excision, scleral melting was followed by fungal keratitis. Endophthalmitis ensued, which rapidly progressed, despite surgi...

PURPOSE To evaluate the usefulness of scleral pneumatonometry as an alternative for corneal measurements of intraocular pressure (IOP) over a broad range of IOPs. DESIGN Prospective, observational cohort study. PARTICIPANTS The study was conducted in the University of California, San Francisco, Retina Clinic between August and November 2013 in 33 adult patients (age range, 34-94 years; mean...

purpose : to assess the efficacy and safety of sutureless punch trabeculectomy as substitute for conventional scleral flap trabeculectomy. methods : in a prospective, randomized study, 44 eyes of 42 patients with primary open angle glaucoma (poag) who were candidate of trabeculectomy were included and randomly assigned into two groups sutureless punch trabeculectomy or conventional scleral flap...

PURPOSE To study the relationship between intraocular pressure (IOP) and the IOP-related stress (force/cross-sectional area) it generates within the load-bearing connective tissues of the optic nerve head. METHODS Thirteen digital, three-dimensional geometries were created representing the posterior scleral shell of 13 idealized human eyes. Each three-dimensional geometry was then discretized...

The sclera is the protective outer layer of the eye. In fishes, birds, and reptiles, the sclera may be reinforced with additional bony elements called scleral ossicles. Teleost fish vary in the number and size of scleral ossicles; however, the genetic mechanisms responsible for this variation remain poorly understood. In this study, we examine the inheritance of scleral ossicles in the Mexican ...

PURPOSE The development of high myopia is associated with scleral thinning and changes in the diameter of scleral collagen fibrils in humans. In the present study, the association between these scleral changes and the losses in scleral tissue that have previously been reported in animal models were investigated to determine the relationship between changes in collagen fibril architecture and th...

PURPOSE Manometric studies have found that intraocular pressure (IOP) rises 116-350 mmHg during scleral depression in surgical settings. No information is available regarding the effect of scleral depression on IOP in routine clinical settings. The aim of this study is to quantify the change in IOP that occurs when scleral depression is performed on normal eyes in a routine clinical setting. ...