BACKGROUND Screening colonoscopy was introduced into the National Cancer Prevention Program in Germany in 2002. We have explored costs and savings of screening and surveillance colonoscopy to investigate whether the induced savings may compensate for the costs of screening. METHODS The study design was a model calculation based on data of a large-scale documentation of screening colonoscopy. ...

BACKGROUND Limited evidence exists on the utilization of surveillance colonoscopy in colorectal cancer (CRC) screening programs. We assessed adherence to physician recommendations for surveillance in opportunistic CRC screening in Germany. METHODS A follow-up study of screening colonoscopy participants in 2007-2009 in Saarland, Germany, was conducted using health insurance claims data. Utiliz...

OBJECTIVE Our study was a randomized, controlled trial to assess a novel strategy that provides comprehensive colorectal cancer screening in a single visit versus traditional sigmoidoscopy and, where appropriate, colonoscopy on a subsequent day. METHODS Consecutive patients referred for screening were randomized to control or so-called "conversion" groups. Patients in the control group were p...

OBJECTIVE To evaluate the implementation of screening colonoscopy amongst first-degree relatives (FDRs) of patients with colorectal cancer (CRC) in Turkey. MATERIALS AND METHODS A total of 400 first-degree relatives (mean(SD)age: 42.5(12.7) years, 55.5% were male) of 136 CRC patients were included in this cross-sectional questionnaire based survey. Data on demographic characteristics, relatio...

BACKGROUND Approximately 15% to 25% of colorectal cancer (CRC) cases have positive family history for disease. Colonoscopy screening test is the best way for prevention and early diagnosis. Studies have found that first degree relatives (FDRs) with low socioeconomic status are less likely to participate in colonoscopy screening program. OBJECTIVES The aim of this study is to determine the ass...

BACKGROUND Compliance rates for colorectal cancer (CRC) screening are much lower than those desired. Appropriate information on CRC risks and screening methods is supposed to stimulate motivation for screening. We aimed to identify parameters associated with the decision for CRC screening and colonoscopy in a population expected to have high awareness of disease prevention. METHODS In a singl...

It has long been believed that colorectal cancer evolves from a precursor lesion, the adenomatous polyp. This concept was based on the elegant pathology studies from the St Mark’s Hospital, London, published by LockhartMummery and Dukes in 1928, and culminating in the concept of the polyp-cancer sequence published in 1975 by Muto and colleagues. The introduction of colonoscopy in the early 1970...

BACKGROUND Patient navigation has been an effective intervention to increase cancer screening rates. This study focuses on predicting outcomes of screening colonoscopy for colorectal cancer among African Americans using different patient navigation formats. METHODS In a randomized clinical trial, patients more than 50 years of age without significant comorbidities were randomized into three n...

Background No randomized, controlled trials of screening colonoscopy have been completed, and ongoing trials exclude persons aged 75 years or older. The Medicare program, however, reimburses screening colonoscopy without an upper age limit. Objective To evaluate the effectiveness and safety of screening colonoscopy to prevent colorectal cancer (CRC) in persons aged 70 to 74 and those aged 75 ...

It has long been believed that colorectal cancer evolves from a precursor lesion, the adenomatous polyp. This concept was based on the elegant pathology studies from the St Mark’s Hospital, London, published by LockhartMummery and Dukes in 1928, and culminating in the concept of the polyp-cancer sequence published in 1975 by Muto and colleagues. The introduction of colonoscopy in the early 1970...