neuroblastoma is the most common extracranial solid tumor in children. the co- occurrence of neuroblastoma and acute lymphoblastic leukemia is rare. we report a rare case of advanced-stage neuroblastoma in a 3.5-year-old girl that was accompanied by acute lymphoblastic leukemia following treatment. her leukemia may have been due to chemotherapy (secondary leukemia) or may have been de novo.

non–hodgkin lymphoma (nhl) causes many deaths worldwide with increasing incidence. non-hodgkin's lymphoma (nhl) may involve the gynecologic tract, and the ovary to be one of the commoner anatomic sites as reported. ovarian involvement by nhl is usually secondary, occurring as a part of systemic disease. the diagnosis is often made incidentally while investigating for gynecological symptoms. we ...

Background: The secondary genetic changes other than the promyelocytic leukemia-retinoic acid receptor (PML-RARA) fusion gene may contribute to the acute promyelocytic leukemogenesis. Chromosomal alterations and mutation of FLT3 (FMS-like tyrosine kinase 3) tyrosine kinase receptor are the frequent genetic alterations in acute myeloid leukemia. However, the prognostic significance of FLT3 mutat...

background: the human aml1 gene, located on chromosome 21, can be fused to the aml1- eight-twenty-one (eto) oncoprotein on chromosome eight, resulting in a t(8;21)(q22;q22) translocation. acute myeloid leukemia (aml) associated with this translocation is considered a distinct aml with a favorable prognosis. due to the various incidences of the translocation, which is associated with geographic ...

Non–Hodgkin lymphoma (NHL) causes many deaths worldwide with increasing incidence. Non-Hodgkin's lymphoma (NHL) may involve the gynecologic tract, and the ovary to be one of the commoner anatomic sites as reported. Ovarian involvement by NHL is usually secondary, occurring as a part of systemic disease. The diagnosis is often made incidentally while investigating for gynecological symptoms. We ...

psoas abscesses could originate from an adjacent source of infection in the abdominopelvic cavity known as a secondary complication of acute appendicitis. however, it is considered as a very rare event when occurring late after the presentation of appendicitis. whether it is the source or complication of acute appendicitis following appendectomy remains unclear. a 25-year-old man was admitted t...

silicosis is considered to be among the occupational lung diseases and associated with sandblasting, mining, quarrying and tunneling. acute silicosis is usually progressive diseaseand despite treatment with corticosteroids it leads to cardio-respiratory failure and death. alveolar silicoproteinosis is one of it’s acute presentations due to exposure to silica dust and lungs filling with proteina...