The use of five fluorouracil (5 FU) as antifibrotic started in the 1960s, in hands of ophthalmologists, to prevent adherence after glaucoma and pterigion surgery. In 1999 Fitzpatric presented his experience in keloids and hypertrophic scars, making a great contribution to their treatment. Fibroblasts main function is collagen synthesis; in vicious scar the amount of collagen is normal, but what...

BACKGROUND There are numerous methods to mold and shape cartilage grafts for use in rhinoplasty. Each technique has advantages and disadvantages. We are going to introduce a new method for cartilage shaping with long lasting effects confirmed by follow up examination and pathologic evaluation. METHODS Grated cartilage was used in 483 patients. For 89 cases, it was wrapped in fascia and in 394...

BACKGROUND Secondary rhinoplasty, one of the final procedures in addressing the stigma of the cleft lip and palate (CLP), has both functional and aesthetic objectives. The way in which physicians evaluate outcomes in surgery concerning aesthetics is changing. Well-designed patient-reported outcome measures to assess health-related quality of life improvements attributable to surgery are increas...

The greatest challenge in primary aesthetic rhinoplasty is the application of advanced anatomical, aesthetic and ethnic principles to an individual case, thereby customizing the procedure to achieve the most natural result for the patient‐individualized treatment plan.[1,2] Specific factors to be noted during the preoperative assessment for the optimization of aesthetic results include the pati...

BACKGROUND The burden of care for children with cleft lip and palate extends beyond primary repair. Children may undergo multiple secondary surgeries to improve appearance or speech. The purpose of this study was to compare the use of secondary surgery between cleft centers. METHODS This retrospective cohort study included 130 children with complete unilateral cleft lip and palate treated con...

The management of nasal deformities especially after rhinoplasty is a challenge. Postsurgical edema may last 6-8 months, causing aesthetic irregularities and nose deformities. The aim of this study is to present the correction of minor nose deformities secondary to rhinoplasty using hyaluronic acid subdermal injections. Eleven patients were treated between 2009 and 2011 with subdermal injection...