Anti-cancer immunotherapy dramatically changes the clinical management of many types tumours towards less harmful and more personalized treatment plans than conventional chemotherapy or radiation. Precise analysis spatial distribution immune cells in tumourous tissue is necessary to select patients that would best respond treatment. Here, we introduce a deep learning-based workflow for cell nuc...

Abstract The permanent magnet motor will inevitably produce cogging torque because of its inherent structure, which cause vibration and noise affect application in certain high-precision applications. Firstly, considering the actual structure stator, a general analytical model is obtained by energy-based approaches. On basis further derivation expressions with different segmented pole structure...

We propose and experimentally demonstrate a novel second-harmonic-generation (SHG) scheme capable of supporting temperature-insensitive phase-matching (PM) at various laser wavelengths. This versatile temperature-insensitive PM is designed by using two cascaded crystals with opposite signs of temperature derivation of phase-mismatch, in which the temperature-induced phase-mismatch in the first ...

August 29, 2013 Type Package Title Threshold Regression Version 1.0.2 Date 2012-11-26 Author Tao Xiao Maintainer Tao Xiao Depends survival, Formula Description Fit a threshold regression model based on the first-hitting-time of a boundary by the sample path of a Wiener diffusion process. The threshold regression methodology is well suited to applications involving survival ...

This paper examines the hypothesis that both stock returns and volatility are asymmetrical functions of past information derived from domestic and US stock market news. By employing a double-threshold regression GARCH model to investigate four major index return series, we find significant evidence to sustain the asymmetrical hypothesis of stock returns. Specifically, evidence strongly supports...

background: investigation of tuberculosis (tb)-specific indices including prevalence of tb, mortality of tb cases excluding hiv, hiv/tb mortality, incidence of tb (all forms), hiv/tb incidence as well as case detection and related trends is a crucial step in evaluation of program performance and strategies success. besides, estimating the number and time of change points for tb incidence can he...

This paper describes a compiler that generates both hardware and controlling software for eld-programmable compute accelerators. By analyzing a source program together with part of its input, the compiler generates VHDL descriptions of functional units that are mapped on a set of FPGA chips and an optimized sequence of control instructions that run on the customized machine. The primary techniq...

background: describing trend in tuberculosis (tb) over time can play an important role to assess the disease control strategies and predict the future morbidity and mortality. this study aimed to determine the incidence trend of smear‑positive pulmonary tuberculosis (sppt) in sub‑age and sex groups during the years of 1995–2012. methods: this retrospective cohort study was performed in 2015 by ...

http://dx.doi.org/10.1016/j.jvcir.2015.08.009 1047-3203/ 2015 Elsevier Inc. All rights reserved. q This paper has been recommended for acceptance by M.T. Sun. ⇑ Corresponding author. Fax: +86 028 61830064. E-mail addresses: [email protected] (Q. Wu), [email protected] (H. Li), [email protected] (F. Meng), [email protected] (K.N. Ngan), eezsy @uestc.edu.cn (S. Zhu). Qingbo Wu a,⇑, Hongli...