BACKGROUND The pathogenesis of some primary humoral immunodeficiencies, such as transient hypogammaglobulinemia of infancy (THI) and immunoglobulin (Ig) A deficiency, remains unknown and can render diagnosis problematic. OBJECTIVE In the present study, we used flow cytometry to analyze peripheral blood B-cell subsets in patients with THI and unclassified hypogammaglobulinemia (UCH), partial I...

No serum IgA was detected in a young male patient suffering from spondylarthropathy (SpA) with bilateral sacroiliitis arthritis, enthesopathy and inflammatory low back pain, whose symptoms occurred in reaction to a sexually induced urethritis. After a period of several months in which the spondylarthropathy was active, disease activity came to a rest. Three years later no progression of the SpA...

than one error simultaneously. We also studied the kind ofoutpatient contml, if any, devoted to these patients. As expected, the greatest percentage of errors was observed in the group of patients without any kind of medical advice (83%). However, practically the same proportion (79%) failed to use the MDIs properly despite the fact that they were under the supervision of medical outpatient car...

than one error simultaneously. We also studied the kind ofoutpatient contml, if any, devoted to these patients. As expected, the greatest percentage of errors was observed in the group of patients without any kind of medical advice (83%). However, practically the same proportion (79%) failed to use the MDIs properly despite the fact that they were under the supervision of medical outpatient car...

than one error simultaneously. We also studied the kind ofoutpatient contml, if any, devoted to these patients. As expected, the greatest percentage of errors was observed in the group of patients without any kind of medical advice (83%). However, practically the same proportion (79%) failed to use the MDIs properly despite the fact that they were under the supervision of medical outpatient car...

Macroamylasaemia and selective IgA deficiency were diagnosed in a 2 year old child who presented with persistent hyperamylasaemia. Macroamylasaemia is an isolated biochemical abnormality caused by aggregation of serum amylase activity with immunoglobulins. Early recognition of macroamylasaemia is important to avoid diagnosing pancreatic disease.

We experienced an 85-year-old male patient with selective IgM deficiency. The average levels of his serum immunoglobulins were as follows: IgG, 1,165 mg/dl, IgA 280 mg/dl, and IgM 17 mg/dl. The subpopulations of peripheral blood lymphocytes in this patient were normal, including normal numbers of IgM-bearing lymphocytes. Normal amounts of cells with cytoplasmic IgM were induced by in vitro addi...

BACKGROUND An association of selective IgA (immunoglobulin A) deficiency in individuals with autism has been previously described. The objective of this study was to examine the incidence of autism spectrum disorders (ASD) in children and siblings of selective IgA deficient patients. OBJECTIVE to assess the likelihood of parents with the most common type of primary immunodeficiency (selective...