BACKGROUND Advanced pancreatic cancer (PC) has very poor prognosis with present treatments, thus necessitating continued efforts to find improved therapeutic approaches. Both preclinical and preliminary clinical data indicate that cytokine-induced killer (CIK) cells are an effective tool against various types of solid tumors. Here, we conducted a study to determine whether CIK cell-based therap...

OBJECTIVE Cognitive behavior therapy (CBT) emerges as the best validated therapeutic approach for children and adolescents who experienced trauma-related symptoms, particularly associated with anxiety or mood disorders. The aim of this study was to evaluate the CBT efficacy among young people exposed to L'Aquila earthquake, in 2009. METHODS one year after the disaster, 39 young subjects as a ...

OBJECTIVE To examine the relative efficacy of family-based cognitive-behavioral therapy (CBT) versus family-based relaxation treatment (RT) for young children ages 5 to 8 years with obsessive-compulsive disorder (OCD). METHOD Forty-two young children with primary OCD were randomized to receive 12 sessions of family-based CBT or family-based RT. Assessments were conducted before and after trea...

Purpose: To examine the effectiveness of group cognitive-behavioral therapy (CBT) based on schema on impulsiveness of substance abusers in Karaj. Materials and Methods: This study was quasi-experimental with pre-test, post-test and control group. The statistical population of this study consisted of male substance abusers who referred to Addiction Treatment Clinics of Karaj in 2010. The sam...

Objective: Diabetes is chronic and debilitating disease that affects all aspects of a person's life. The purpose of this study was to compare the effectiveness of compassion focused (CFT)-acceptance commitment (ACT) combined therapy with cognitive-behavioral therapy (CBT), on interpersonal forgiveness in women with type II diabetes. Materials and Methods: This was of quasi- experimental study ...

background: emotion-focused cognitive behavioral therapy (ecbt) is a new form of cbt with emotion regulation components. this form of treatment is suggested to be employed to improve dysregulation of anxiety and other kind of emotions in anxious children.this study observed and compared the effectiveness of cbt and ecbt on anxiety symptoms; sadness and anger management;and cognitive emotion reg...

This study compared individual (I) to group (G) formats of cognitive-behavioral therapy (CBT) and interpersonal psychotherapy (IPT) for the treatment of depression in adolescents. One hundred and 12 Puerto Rican adolescents were randomized to four conditions (CBT-I, CBT-G, IPT-I, IPT-G). Participants were assessed at pretreatment and posttreatment with structured interviews to establish diagnos...

OBJECTIVE To evaluate the efficacy of cognitive behavior therapy (CBT), adapted to meet the unique needs of individuals with acquired brain injury (ABI), and modified for both group and telephone delivery. DESIGN Matched-controlled trial, with multiple measurements across participants, including pretreatment baseline assessment plus posttreatment and 1-month follow-up. SETTING Outpatient co...

BACKGROUND Since long ago it has been asserted that internal conflicts are relevant to the understanding and treatment of mental disorders, but little research has been conducted to support the claim. The aim of this study was to test the differential efficacy of group cognitive behavioral therapy (CBT) plus an intervention focused on the dilemma(s) detected for each patient versus group indivi...