432 Patterns of Sensitization to Common Food and inhalant Allergens and Allergic Symptoms in Preschool Children Man Yong Han, MD. Pediatrics, CHA University College of Medicine, Seoul, South Korea. Background: The prevalence of sensitization to allergens and symptoms of allergic disease differ with regard to age, but the relationship is poorly understood. This study aimed to investigate the pat...

BACKGROUND Flooding may affect aeroallergen sensitization. OBJECTIVE To evaluate aeroallergen sensitization in children with asthma and/or allergic rhinitis (AR) by skin prick test (SPT) before and after the great flood of 2011 in Bangkok, Thailand. METHODS The study was performed retrospectively in asthma and/or AR children (aged 0-18 years) in Siriraj Hospital, Bangkok, Thailand from 2009...

432 Patterns of Sensitization to Common Food and inhalant Allergens and Allergic Symptoms in Preschool Children Man Yong Han, MD. Pediatrics, CHA University College of Medicine, Seoul, South Korea. Background: The prevalence of sensitization to allergens and symptoms of allergic disease differ with regard to age, but the relationship is poorly understood. This study aimed to investigate the pat...

The lateral hypothalamus (LH) has long been known to implicate in the addictive behaviors of drugs of abuse. The ventral tegmental area (VTA) is a major area of the mesolimbic system that is strongly involved in the development of morphine sensitization. The current study aimed to examine the role of intra-VTA orexin receptors in the LH stimulation-induced sensitization to the antinociceptive r...

Repeated exposure to cocaine increases the density of dendritic spines on medium spiny neurons in the nucleus accumbens (Acb) and pyramidal cells in the medial prefrontal cortex (mPFC). To determine if this is associated with the development of psychomotor sensitization, rats were given daily i.p. injections of 15 mg/kg of cocaine (or saline) for 8 days, either in their home cage (which failed ...

introduction: the influence of ascorbic acid on the nicotine-induced conditioned place preference (cpp) and behavioral sensitization was investigated in the present study. methods: in a pilot study, place conditioning and locomotor activity were investigated after nicotine (0.25, 0.5, 0.75, 1, 1.5 and 2 mg/kg) or ascorbic acid (1, 10, 100 and 1000 mg/kg) administration. different doses of ascor...

Allergic diseases are on the rise in Asia. Aeroallergen exposure is a strong risk factor for sensitization, development and severity of atopic diseases, especially in the Asian paediatric population. Geographical and seasonal variations in aeroallergen sensitization are seen even within Asian countries and changes in aeroallergen sensitization patterns have been observed over time. Some possibl...