anaerobic bacteria are well known causes of sepsis in adults but there are few studies regarding their role in neonatal sepsis. in an attempt to define the incidence of neonatal anaerobic infections a prospective study was performed during one year period. a total number of 400 neonates under sepsis study were entered this investigation. anaerobic as well as aerobic cultures were sent. the pati...

OBJECTIVE To study changes in blood lipid metabolism in sepsis patients, especially high-density lipoprotein cholesterol (HDL-C) changes in the diagnosis of sepsis and the type of bacteria involved. METHODS Two-hundred-twenty cases of patients with febrile infections were divided into local infection, systemic inflammatory response syndrome or sepsis (sepsis) group. For controls, 81 cases of ...

bacterial sepsis is one of the most common causes of mortality and morbidity in neonates. it has been recognized a gradual change in spectrum of organisms responsible for neonatal sepsis. in this study we have evaluated changing trend of incidence and antibiotic susceptibility in neonatal late - onset sepsis (los) in 2-periods. this study is based on results of blood culture in neonatal late-on...

Nearly 100 years ago, antimicrobial peptides (AMPs) were identified as an important part of innate immunity. They exist in species from bacteria to mammals and can be isolated in body fluids and on surfaces constitutively or induced by inflammation. Defensins have anti-bacterial effects against Gram-positive and Gram-negative bacteria as well as anti-viral and anti-yeast effects. Human neutroph...

Sepsis caused by gram-negative bacteria and that caused by gram-positive bacteria often manifest similar clinical features. We investigated plasma proinflammatory cytokine profiles in patients with sepsis due to gram-positive and gram-negative bacteria and studied the cytokine production and differential gene regulation of leukocytes stimulated ex vivo with Escherichia coli lipopolysaccharide o...

PURPOSE The aim of this study was to explore the risk factors, clinical symptoms, hematological parameters, causative pathogen and antibiotic susceptibility of neonatal sepsis in a Chinese NICU. METHODS A retrospective survey was conducted on 116 cases of neonatal sepsis in NICU at the Maternal and Child Care Hospital in Shenzhen, China from January 2009 to December 2012. Patients were divide...

Background: Sepsis or blood stream infection is a clinical lethal syndrome with severe systemic inflammatory response to infection, if not treated quickly, is associated with dangerous consequences and high morbidity and mortality. The traditional and conventional method for identification of sepsis is blood culture method which is so time-consuming and long that it eliminates the possibility o...

Introduction: Procalcitonin is known as a marker of infection and indicator for severity infections. In sepsis, elevated procalcitonin levels in blood have significant value that can be used sepsis biomarker. The aim this study was to determine the mean difference Gram-positive Gram-negative bacterial patients.Methods: This quantitative method with cross sectional approach. sample were patients...