It has been suggested that copper ion is involved in the pathogenesis of various diseases. The aim of this study is to examine the association of serum copper levels and glycemic control in patients with type 2 diabetes. We recruited a total of 132 patients with type 2 diabetes, and measured their serum copper levels by atomic absorption spectrometry. Serum copper levels were positively correla...

BACKGROUND Older subjects have a high risk of developing zinc and copper deficiencies. AIM To determine the prevalence of copper and zinc deficiencies in adults aged over 60 years, living in Metropolitan Santiago. SUBJECTS AND METHODS Analyses were performed using anonymous serum samples from older subjects living in Santiago, Chile, who participated in the multicenter project SABE. Of the ...

In addition to copper bound to ceruloplasmin and to albumin, there is a third small fraction of copper in human serum that is bound to amino acids. The amino acid-bound fraction of copper is in equilibrium with albumin-bound copper, and both fractions are probably in equilibrium with ionic copper. Of the 23 amino acids that are known to be in human serum, a substantial number were shown (in phy...

BackgroundMany studies reported that copper, zinc and magnesium play important roles in the pathogenesis and development of neonatal hyperbilirubinemia. Exchange transfusion and intensive phototherapy are known two modalities of therapy for severe neonatal hyper bilirubinemia, but the effect of them on those trace elements is unknown.Materials and MethodsCopper, Zinc and Magnesium serum levels ...

adverse outcomes of pregnancy increase among women with high density of hemoglobin. this study evaluates the effects of iron supplementation on serum copper level in pregnant women with hemoglobin higher than 13.2 g/dl. sixty two pregnant women with hemoglobin >13.2 g/dl and normal serum copper levels in their 13-18 weeks of gestation were randomized into case and control groups. from 20 th wee...

This study evaluated the effect of menopausal hormone therapy (MHT) on serum concentration of copper in postmenopausal women depending on passive or active exposure to tobacco smoke or lack thereof. The study included healthy postmenopausal women aged 42-69 years, who used (n = 76) or did not use (n = 76) MHT. Salivary cotinine and serum copper concentrations were determined in all the study su...

Serum zinc and copper concentrations of 156 healthy children (6-12 years old) were measured by the atomic absorption spectrophotometric method. The average serum zinc concentration was 92 +/- 13 mug/100 ml (mean +/- S.D.) with a range of 62-127 mug/100 ml. No statistically significant age or sex differences were found in serum zinc levels. The mean serum copper level was 109 +/- 17 mug/100 ml w...

OBJECT Anemia and leukopenia caused by copper deficiency are well-documented consequences of long-term total parenteral nutrition. We measured the serum copper levels of bed-ridden patients receiving enteral feeding, and evaluated optical and ultrastructural features of bone marrow before and after copper supplementation. PATIENTS AND METHODS Serum samples were obtained from 15 bed-ridden eld...

Objective: To investigate the serum concentrations of copper (Cu), zinc (Zn) and copper/zinc ratio (Cu/Zn) in patients with ovarian cancer and benign ovarian lesions. Methodology: The study included 50 patients, with ovarian cancer (malignant group) and 50 patients with benign ovarian lesions (benign group). After overnight fasting, blood samples were collected. The concentrations of Cu and Zn ...