background: progress in the field of biology and biochemistry has led to the discovery of numerous bioactive peptides and proteins in the last few decades. delivery of therapeutic proteins/peptides has received a considerable amount of attention in recent years. methods: in this study, a two-step desolvation method was used to produce biodegradable hydrophilic gelatin nanoparticles (gnp) as a d...

background: the aim of the present study was to evaluate the efficacy of autologous serum eye drop in treatment of recurrent corneal epithelial defect. m aterials and methods: fourteen patients with recurrent corneal epithelial defect were studied. autologous serum was prepared from the patients and diluted in 20% normal saline. the patients were instructed to use the autologous serum every six...

a three-fold decrease of the in vitro ability of serum proteins to bind naproxen was shown in patients with cirrhosis of the liver compared to healthy individuals. this decrease was caused by quantitative changes in serum proteins in the sera of patients with liver damage. lower doses of naproxen are therefore suggested in the treatment of patients with liver dysfunction.

abortion is the termination of a pregnancy by the removal or expulsion of a fetus or embryo from the uterus, resulting in or caused by its death. missed abortion is the most common dangerous condition in pregnancy. an abortion can occur due to maternal complications, chronic disease, endocrine disorders, abortificient drugs, radiation, heavy metals and toxins. the study population consisted of ...

quantitative serum level measurements of gc , cp , c3 , igg , iga and 1gm were carried out on 102 patients with esophageal carcinoma following laryngectomy, in comparison with 66 healthy individuals as controls, in gonbad area, north east of iran. the procedure of radioinimuno-diffusion by standard m partigen plates was used for the measurements. a significant decrease was observed in gc level ...

hypokalemic disease is a disorder in which the amount of serum’ s potassium declines and the patient faces limbs weakness. in this disease, eye muscle and respiratory muscles rarely become involved and death may follow due to respiratory paralysis and heart conducting disturbances. since this disease is treatable and progressive weakness can be prevented, therefore in the study conducted we att...

background: one of the most common endocrine problems in major beta-thalassemia is hypothyroidism (ht). the aim of this study was to evaluate thyroid function status in major beta-thalassemia patients older than 10 years old. methods: this cross sectional study was carried out on thalassemia major patients registered on thalassemia center of amirkola children hospital in babol. a questionnaire ...

background patients, who survived from shotgun injuries, often have some retained lead pellets in their bodies. several cases of lead toxicity have been reported regarding these patients. objectives this study seeks to compare the serum lead level in patients who have retained lead pellets in their bodies with the control group. patients and methods in this case-control study, we gathered the s...

deproteinisation with acetonitrile (along with methanol or other reagents) is a useful and rapid technique in analysis of drugs or their metabolites in human serum. in this paper application of this simple technique in biopharmaceutical analysis using capillary electrophoresis (ce) is evaluated. some drugs with different ionic and protein binding properties were selected and dissolved in human ...

serum ferritin (sf) levels in 734 seven-year-old children was measured by a radioimmuno assay method, and its possible relation-ship with hemoglobin, hematocrit and mchc was investigated. the results showed there was positive correlation between sf with hemo-globin, hematocrit and mchc values.