This study is written in a way to stress the importance of introducing the active force generated by the myocardium in the formalism describing the pressure-volume relation (PVR) in the left ventricle. Various clinical applications of the end-systolic pressure-volume relation (ESPVR) are also discussed. Attention is given to the calculation of the ejection fraction (EF) and the myocardial longi...

To determine whether regional wall motion abnormalities exist or contribute to left ventricular dysfunction, we obtained two-dimensional echocardiograms in 12 athletes before (baseline), immediately after (race finish), and 1 day after (recovery) the Hawaii Ironman Triathlon (a 3.9-km swimming, 180.2-km bicycling, and 42.2-km running event). Left ventricular short-axis and apical four-chamber v...

Background: Beta-thalassemia major is a severe and lethal hemolytic anemia. Regular transfusion is necessary for avoidance of its complications but it may end to cardiac involvement secondary to iron overload. Angiotensin converting enzyme inhibitors (ACEIs) are useful medications even in early stages of heart failure. We studied the effects of two common ACEIs on improvement of heart function ...

abstract: large quantities of beef and mutton tallow are available in iran every year. if these products are processed and formulated properly and scientifically, the need to import oils and fats in a substantial quantities might be reduced. the aim of this study is to fractionate beef tallow into different fractions and carry out physical and chemical tests on each isolated fraction. beef fat ...

BACKGROUND: Bone marrow-derived mesenchymal cellscan transdifferentiate into Cardiomyocyte cells and improveheart function after transplantation. Since biomaterials canimprove the cell retention in the site, cell survival and differentiation,heart tissue engineering is now being explored as anapplied solution to support cell-based therapies and increasetheir efficacy for myocardial diseases. Ch...

background: beta-thalassemia major is a severe and lethal hemolytic anemia. regular transfusion is necessary for avoidance of its complications but it may end to cardiac involvement secondary to iron overload. angiotensin converting enzyme inhibitors (aceis) are useful medications even in early stages of heart failure. we studied the effects of two common aceis on improvement of heart function ...

In hypertensive patients with left ventricular hypertrophy, antihypertensive treatment induces changes in left ventricular structure and function. However, less is known about gender differences in this response. Baseline and annual echocardiograms until the end of study or a primary end point occurred were assessed in 863 hypertensive patients with electrocardiographic left ventricular hypertr...

In order to determine the severity of contraction abnormalities in acute myocardial infarction and their response to sublingual nitroglycerin, 23 patients were studied by radionuclide angiography within 6-24 hours after the onset of chest pain. Radionuclide angiograms were obtained in the right anterior oblique projection before and after nitroglycerin and segmental shortening was determined us...

BACKGROUND Dyssynchrony of myocardial deformation is usually described in terms of variability only (e.g. standard deviations SD's). A description in terms of the spatio-temporal distribution pattern (vector-analysis) of dyssynchrony or by indices estimating its impact by expressing dyscoordination of shortening in relation to the global ventricular shortening may be preferential. Strain echoca...

OBJECTIVE To study the sequential shortening of Torrent-Guasp's 'rope-heart model' of the muscular band, and analyze the structure-function relationship of basal loop wrapping the outer right and left ventricles, around the inner helical apical loop containing reciprocal descending and ascending spiral segments. METHODS In 24 pigs (27-82 kg), temporal shortening by sonomicrometer crystals was...