Background: Only 17 cases of neonatal submandibular sialadenitis have been described in neonates. These infections are frequently caused by gram-positive cocci. We unexpectedly observed multiple cases of sialadenitis and cervical adenitis in our regional NICU within a few years, as staphylococcal aureus infections have become more prevalent in the hospital and community. Therefore, we postulate...

OBJECTIVE To determine whether unique patterns of care are evolving in the United States compared with Germany in endoscopic management of chronic sialadenitis. DESIGN Comparison of consecutive series of patients. SETTING Academic tertiary salivary referral centers in Germany and the United States. PATIENTS A total of 446 patients having chronic sialadenitis treated with salivary endoscop...

BACKGROUND Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induces apoptosis of tumor cells but not normal cells; its role in normal non-transformed tissues is unknown. OBJECTIVE To evaluate the role of apoptosis mediated by TRAIL and TRAIL-receptor (TRAIL-R) system in lymphocytic sialadenitis in patients with Sjögren's syndrome. METHODS The expression of TRAIL and TRAIL-R1,...

BACKGROUND IgG4 related disease rarely affects the salivary glands and clinically is often confused with salivary gland malignancy. METHOD This is a retrospective study comprising 137 cases of chronic sialadenitis diagnosed in a histopathology department over 4 years. The morphology was assessed by reviewing the histology slides and the incidence of IgG4 related sclerosing sialadenitis was ca...

A ten-year-old indoor, castrated male Cardigan Welsh Corgi (Canis familiaris) presented with the chief complaints of chronic vomiting, retching, hypersalivation, and bilateral submandibular masses for two months. The systemic examinations, including serum chemistry, radiography, ultrasonography, fluoroscopy, were unremarkable. fine-needle aspiration revealed sialadenitis. Broad-spectrum antibio...

This is the first reported case of a marginal zone lymphoma with prominent lymphoepithelial sialadenitis of heterotopic salivary gland tissue. A 67-year-old female patient presented neck masses. Neck 3-dimensional computed tomography suggested Sjögren’s syndrome in both parotid glands and also revealed several cervical lymph nodes enlargement. Histologic findings of superficial parotid glands w...