نتایج جستجو برای: sib families
تعداد نتایج: 125551 فیلتر نتایج به سال:
Several candidate genes for non-insulin-dependent diabetes mellitus (NIDDM) map on chromosome 20, including the phosphoenolpyruvate carboxykinase gene (PCK1) and one of the maturity onset diabetes of the young genes (MODY1). Thus, we have investigated the entire long arm of chromosome 20. Linkage analyses were conducted in a total sample of 148 NIDDM families (301 NIDDM sib pairs) and in a subs...
The efficiency of marker-assisted prediction of phenotypes has been studied intensively for different types of plant breeding populations. However, one remaining question is how to incorporate and counterbalance information from biparental and multiparental populations into model training for genome-wide prediction. To address this question, we evaluated testcross performance of 1652 doubled-ha...
Formulae for calculating the variances and covariances of estimates of genetic variance or covariance from offspring-parent and sib covariance data are presented. The model consists of a one-way classification of families with unequal numbers of offspring, where normally distributed traits x (a parental measure), y and z (offspring measures) are recorded. Procedures for pooling offspring-parent...
Sixteen microsatellite loci isolated from Halesia tetraptera are described. All 16 are polymorphic, with four to 13 alleles across 15–19 members of a single half-sib family. Heterozygosity ranged from 0.067 to 1. One locus departs significantly from Hardy–Weinberg equilibrium in our test family. The test population shows significant heterozygote deficiency at this and two other loci. Thirteen l...
A genome scan was conducted in two US Holstein half-sib families to identify quantitative trait loci (QTL) affecting milk production and conformation traits using the granddaughter design. The sires of the two studied families were related as sire and son and had 96 and 212 sons respectively. A total of 221 microsatellite loci were scored in both families. Statistical analysis was performed usi...
BACKGROUND Monoamine oxidase B (MAO-B) degrades catecholamines in presynaptic nerve endings and is also active in platelets. There is evidence to suggest that platelet MAO-B activity level is controlled by a major genetic locus distinct from the structural gene on the X chromosome. To expand on a prior report, new linkage analyses for platelet MAO-B activity have been performed on the previousl...
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