نتایج جستجو برای: significant contribution

تعداد نتایج: 1401391  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2004
Weili Huang Yvonne S Lin Donavon J McConn Justina C Calamia Rheem A Totah Nina Isoherranen Mary Glodowski Kenneth E Thummel

CYP3A4 and CYP3A5 exhibit significant overlap in substrate specificity but can differ in product regioselectivity and formation activity. To further explore this issue, we compared the kinetics of product formation for eight different substrates, using heterologously expressed CYP3A4 and CYP3A5 and phenotyped human liver microsomes. Both enzymes displayed allosteric behavior toward six of the s...

Journal: :Monthly Notices of the Royal Astronomical Society 2017

2017
Htet Myet Win Maung Saw Saw Petros Isaakidis Mohammed Khogali Anthony Reid Nguyen Binh Hoa Ko Ko Zaw Saw Thein Si Thu Aung

BACKGROUND It is estimated that the standard, passive case finding (PCF) strategy for detecting cases of tuberculosis (TB) in Myanmar has not been successful: 26% of cases are missing. Therefore, alternative strategies, such as active case finding (ACF) by community volunteers, have been initiated since 2011. This study aimed to assess the contribution of a Community Based TB Care Programme (CB...

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