Background & Objectives: Streptozotocin (STZ) is used for induction of Type-1 diabetes mellitus in animal models. Its beta-cytotoxic action results in sudden release of insulin leading to severe hypoglycaemia and even mortality. However, its sensitivity varies with species. Present investigation was aimed at studying STZ induced acute clinical effects in rabbits. Methods: Str...

background: workers in cotton industry are occupationally exposed to various dust-related hazards. the nature of these agents and the respective exposure levels depend on the cotton industry specific sector. these exposures could be associated with respiratory symptoms and changes in lung function parameters. objective: to evaluate associations between occupational exposure and respiratory func...

The interplay between state negative affect (SNA) and somatic symptoms is well-established in daily life, but the nature of the association is unclear. Questions remain regarding the role, if any, that SNA plays apart from trait negative affect (TNA), the direction of the association, and whether the relationship with SNA varies according to symptom type. Associations between three constellatio...

clinical assessment of distal symmetric polyneuropathy (dpn) involves the evaluation of symptoms and signs. although there are numerous tools to evaluate dpn, there is still a need to determine the most sensitive, specific, and accurate tests to detect dpn in a busy outpatient clinical setting. a total of 107 patients with type 2 diabetes were examined using michigan neuropathy screening instru...

Three cases of decompression illness are reported. Two patients presented with joint pain and skin signs, while one patient presented with joint pain and neurological signs and symptoms. The patients received emergency recompression therapy in a Hong Kong clinic, using a monoplace hyperbaric chamber. All three patients were treated successfully and no residual signs or symptoms were evident on ...

The purpose of the study was to investigate concussion history, knowledge, injury identification, and management strategies among athletes, coaches, and medical staff in Italian club level football (soccer) clubs. Surveys (N=727) were distributed among Italian football clubs. Athletes' surveys were designed to evaluate athlete knowledge of concussive signs and symptoms and injury reporting. Coa...

Representative population random sampling plans were used for the recruitment of participants for all study sites. As of June 2011, 20 sites (in 18 countries) had completed data collection and are included in this analysis: Guangzhou (China), Adana (Turkey), Salzburg (Austria), Cape Town (South Africa), Reykjavik (Iceland), Hannover (Germany), Krakow (Poland), Bergen (Norway), Vancouver (Canada...

We present a case where a diagnosis of advanced HIV led to many other diagnoses but more importantly life-threatening multivariant Castleman's disease which is rare and was successfully treated. This case highlights the importance of questioning and challenging investigations when it does not fit with the clinical picture. Multidisciplinary teams are crucial and always seek expert advice if uns...

Congenitally defective metabolic pathways adversely affect the quality of life of patients as well as their care givers. Early diagnosis is therefore vital. Frequently, radio-imaging alone raises a strong suspicion and sometimes even provides conclusive evidence of defective metabolic pathways, when the patient presents with signs and symptoms that clinically fail to lead to a definitive diagno...