Stable radicals detectable by electron paramagnetic resonance (EPR) may be use in the investigation of early events in cell-particle toxicity. Piperidine-N-oxyl derivatives (nitroxides), covalently linked to the surface of a high surface area silica (used as model solid for the technique), served as probes in the investigation of the effects of incubation of silica particles with mesothelial ce...

Asymmetric nanocomposite particle pairs of polystyrene and silica were prepared via one-step miniemulsion polymerization for the first time. The transmission electron microscopy images showed that these nanocomposite particle pairs were monodisperse and highly asymmetric in morphology. The key to obtaining the asymmetric nanocomposite particle pairs was the combination of miniemulsion polymeriz...

Extensive application of silica nanoparticles (SNPs) in various industrial products has led to the development of silica extraction methodologies out of various waste products. Rice husk is an agricultural waste with a high content of amorphous silica. However, the presence of metal ion impurities and unburned carbon in the rice husk content may present an adverse effect on product color and pu...

Adsorbent properties and aqueous characteristics are very important parameters in the removal efficiency (RE) of environmental pollutants. The main goal of this study was to investigate the effects of pH, particle size and porosity of raw rice husk and its silica on removing lead and hexavalent chromium (Cr+6) from aqueous solution. The raw rice husk was collected from north of Iran and the ric...

BACKGROUND Occupational exposure to crystalline silica is a well-established occupational hazard. Once in the lung, crystalline silica particles can result in the activation of alveolar macrophages (AM), potentially leading to silicosis, a fibrotic lung disease. Because the activation of alveolar macrophages is the beginning step in a complicated inflammatory cascade, it is necessary to define ...

Silica inhalation can induce respiratory disease. Iron is suspected of playing an important role in silica-mediated respiratory toxicity, but unambiguously determining its role has been hampered by incomplete characterization, use of high particle doses, and lack of understanding of proinflammatory mechanisms. In this study, we investigated a novel hypothesis for the mechanism of silica particl...

Background: Millions of workers globally are afflicted by pneumoconiosis, a disease caused by inhaling dust or particles. A particularly prevalent form is silicosis, caused by inhaling silica particles. The Chinese herbal medicine kombucha, which contains Gluconacetobacter xylinus and yeasts, can effectively clear dust from rats’ lungs. The study presented here assessed the potential effectiven...

PURPOSE The effects of particle size on the tissue distribution and excretion kinetics of silica nanoparticles and their biological fates were investigated following a single oral administration to male and female rats. METHODS Silica nanoparticles of two different sizes (20 nm and 100 nm) were orally administered to male and female rats, respectively. Tissue distribution kinetics, excretion ...

the goal of this research is to determine the feasibility of loading rifampin into mesoporous silica nanoparticles. rifampin was selected as a model lipophilic molecule since it is a well-documented and much used anti tuberculosis drug. the mesoporous silica nanoparticles were prepared by using tetraethyl ortho silicate and cetyltrimethyl ammonium bromide (as surfactant); the prepared nanoparti...

This research aims at providing evidence of particle suspension contributions to emulsion stability, which has been cited as a contributing factor in crude oil recovery by low-salinity waterflooding. Kaolinite and silica particle dispersions were characterized as functions of brine salinity. A reference aqueous phase, representing reservoir brine, was used and then diluted with distilled water ...