Contact lens induced ulcerative keratitis is a serious complication which can be devastating for the patient if treatment is delayed. Extended wear is the commonest cause of microbial keratitis in contact lens wear. New extended wear silicone hydrogel contact lenses have higher oxygen transmissibility so that they can be worn continuously for 30 days. They can also be used as bandage contact le...

Contact lens induced ulcerative keratitis is a serious complication which can be devastating for the patient if treatment is delayed. Extended wear is the commonest cause of microbial keratitis in contact lens wear. New extended wear silicone hydrogel contact lenses have higher oxygen transmissibility so that they can be worn continuously for 30 days. They can also be used as bandage contact le...

Contact lens induced ulcerative keratitis is a serious complication which can be devastating for the patient if treatment is delayed. Extended wear is the commonest cause of microbial keratitis in contact lens wear. New extended wear silicone hydrogel contact lenses have higher oxygen transmissibility so that they can be worn continuously for 30 days. They can also be used as bandage contact le...

The relationship between corneal edema and hydrogel lens oxygen transmissibility was examined for both daily and extended contact lens wear by measuring the corneal swelling response induced by a variety of contact lenses over a 36-hr wearing period. The relationships derived enable average edema levels that occur with daily and extended wear in a population of normal young adults to be predict...

The process of any contact lens related keratitis generally starts with the adhesion of opportunistic pathogens to contact lens surface. This article focuses on identifying the factors which have been reported to affect bacterial adhesion to contact lenses. Adhesion to lenses differs between various genera/species/strains of bacteria. Pseudomonas aeruginosa, which is the predominant causative o...

Protein deposition is one of the most frequent contaminants occurring on hydrophilic contact lenses and may modify the lens optical properties. The silicone-hydrogel contact lenses usually adsorb a lower amount of proteins than the conventional hydrogel ones. However it is important to study the influence of protein deposits on some silicone-hydrogel contact lenses properties, such as UV-Visibl...

OBJECTIVE To investigate the incidence of adverse events related to the use of varying silicone hydrogel contact lens and lens solution combinations. METHODS Individuals with myopia (N = 558) participated in 1 or more of approximately 40-participant trials in a matrix of 20 silicone hydrogel contact lens and lens-solution combinations. Visits were at baseline, 2 weeks, 1 month, and 3 months. ...

PURPOSE The purpose of this work was to develop an enzymatic method of quantification of cholesterol and cholesterol esters derived from contact lenses, both in vitro and ex vivo. METHODS Lotrafilcon B (O2 Optix; CIBA Vision, Inc., Duluth, GA) and galyfilcon A (Acuvue Advance; Vistakon, Inc., Jacksonville, FL) silicone hydrogel contact lenses were independently incubated in cholesterol oleate...

PURPOSE to evaluate changes in tear metrics and ocular signs induced by six months of silicone-hydrogel contact lens wear and the difference in baseline characteristics between those who successfully continued in contact lens wear compared to those that did not. METHODS Non-invasive Keratograph, Tearscope and fluorescein tear break-up times (TBUTs), tear meniscus height, bulbar and limbal hyp...