نتایج جستجو برای: single channel recording

تعداد نتایج: 1110926  

Journal: :research in pharmaceutical sciences 0
h sadraei sr abtahi m nematollahi k karbalaie f karamali h baharvand

embryonic stem cells are capable of differentiating to variety of cell tissues including cardiomyocytes. this developmental change is accompanied with a great deal of ion channel expression and functions. mouse stem cell derived cardiomyocytes were prepared and separated to yield isolated single cell suspension for cell current recording. in the present study some properties of the k + -current...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه هرمزگان - دانشکده کشاورزی و منابع طبیعی 1393

در تحقیق حال حاضر، با بهره گیری از این تکنولوژی به بررسی تغییرات کاربری اراضی و پوشش زمین و اثر آن بر دمای سطحی شهر گرگان استان گلستان، طی سال های 1986 و 2010 پرداخته شده است. بدین منظور از تصاویر tm و etm+ در این تحقیق استفاده گردید. پس از انجام عملیات پیش پردازش، با استفاده از الگوریتم حداکثر احتمال همانندی تصاویر به چهار کلاس کلی (1- جنگل، 2- منطقه شهری و ساخت و ساز ، 3- کشاورزی، 4- آب) طبقه...

2012
Ronald Wilders Andrew Fielding

Contents 1. Introduction 2. Experimental techniques 2.1. Ion concentrations 2.2. Whole-cell recording 2.3. Current clamp and voltage clamp 2.4. Voltage clamp experiments 2.5. Recording single channel activity 2.6. Rundown 2.7. Effect of intracellular calcium buffering 2.8. Heterogeneity of cardiac cells 2.9. Electrical pathway between cells 3. Modeling the cell membrane and ion channels 3.1. El...

Journal: :physiology and pharmacology 0
sahar golabi majid hassanpour-ezati dept. biology, science school, shahed university, tehran, iran kambiz rohampour

introduction: previously, we demonstrated that i.p. injection of aqueous extract prepared from aerial parts of drosera spatulata (droseraceae) can induced remarkable analgesia in both phases of formalin test in rats. because, analgesia induced in acute phase of formalin test mainly mediated by activation of central analgesic mechanisms and also paragigantocellularis (pgi) nucleus is part of bra...

2013
Ryuji Kawano Yutaro Tsuji Koji Sato Toshihisa Osaki Koki Kamiya Minako Hirano Toru Ide Norihisa Miki Shoji Takeuchi

Although ion channels are attractive targets for drug discovery, the systematic screening of ion channel-targeted drugs remains challenging. To facilitate automated single ion-channel recordings for the analysis of drug interactions with the intra- and extracellular domain, we have developed a parallel recording methodology using artificial cell membranes. The use of stable lipid bilayer format...

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