Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs due to an underlying gammopathy. Case presentation: Our patient was an 86-year-old man with macroglossia, ecchymotic patches and bullous lesion...

A 9-year old boy had severe muscle weakness and typical skin rash and EMG with diagnosis of dermatomyositis associated with erythrodermia with islands of normal skin and palmoplantar hyperkeratosis, which was reported. As PRP in skin biopsy. Association dermatomyositis with PRP is very rare.

1.1 Skin biopsy The skin biopsy is a relatively simple, but essential procedure in the managment of skin disorders. As a diagnostic method, skin biopsy is most commonly used in dermatology rather than in other medical specializations. The most common indication is to diagnose or exclude cutaneous malignancies. Properly performed, it may confirm a diagnosis, remove cosmetically unacceptable lesi...

Dermatological disorders are a frequent presenting feature of HIV infection and/or AIDS. More than 90% of HIV-infected patients will suffer from one or more skin diseases during the course of their illness. This trend is reflected in the increasing number of skin biopsies from HIV-positive patients in those parts of the world where HIV infection/AIDS is highly prevalent. Histopathologists are t...

creased dural venous sinus pressure or a defect in the arachnoid villi. The possibility of dural venous sinus thrombosis was ruled out in this case by MR examination that showed the venous sinuses to be widely patent. As suggested by the MR findings in this patient, low hemoglobin levels may result in compensatory changes in cerebral blood volume, leading to increased intracranial pressure. Thi...

BACKGROUND The number of core biopsies done for breast abnormalities is increasing. The risk of skin seeding resulting from core biopsy is unknown. METHODS Consecutive patients diagnosed with breast cancer were studied. The skin and subcutaneous fat surrounding the site of core needle penetration were excised and studied by routine histologic staining. Findings were correlated with other clin...

A skin biopsy is one of the most frequently performed procedures in the dermatology outpatient clinic, but doctors often do not consider the cognitive impact of the biopsy procedure. Based on "terror management theory," we reasoned that a skin biopsy increases patient compliance by unconsciously stimulating mortality salience. To study this hypothesis, trust toward doctors, authoritarian person...