Gastrointestinal stromal tumors (GISTs) are rare, but are the most common mesenchymal neoplasm of the gastrointestinal tract. The most common sites of metastasis are liver and peritoneum, while bone metastasis is rare. We report on a patient with skull metastasis after seven years of treatment with imatinib for metastatic GIST. She underwent metastasectomy consisting of craniectomy with excisio...

Papillary thyroid carcinoma (PTC), which is characterized by low incidence of distant metastases, is a common subtype of thyroid carcinoma. Metastases of the clear cell variant (CCV), one of the many PTC variants, are rare. A 73-year-old woman with a 2-year history of a growing subcutaneous tumor in the right temporal region of her skull was admitted to our hospital; the tumor was initially spe...

BACKGROUND Our aim was to grade MRI-detected skull-base invasion in nasopharyngeal carcinoma and evaluate the prognostic value of the grading. METHODS The MRI scans and medical records of 924 patients with histologically diagnosed nondisseminated nasopharyngeal carcinoma were reviewed retrospectively. RESULTS MRI-detected skull-base invasion was not found to be an independent prognostic fac...

A bout 7 cases of esophageal carcinoma per 100 000 men are diagnosed in Taiwan, with variable metastatic tendency to other parts of the body. Esophageal carcinoma frequently metastasizes to the lungs and liver, although the metastatic deposits to the bone are infrequent and metastatic disease in the skull is extremely rare. We encountered a patient with a metastasis of esophageal carcinoma over...

BACKGROUND Skull and intracranial metastases from hepatocellular carcinoma (HCC) have seldom been reported. A skull metastasis of HCC with a tumor bleeding resulting in spontaneous subdural hematoma (SDH) is extremely unusual. We report the first case of acute spontaneous SDH in a 69-year-old woman who presented with acute onset of headache, because of tumor bleeding caused by skull metastasis ...

BACKGROUND There is a vast discrepancy between the incidence of skull base metastases reported in vivo and at autopsy. Asymptomatic character or unspecific symptoms make the diagnosis difficult, particularly in patients with no history of cancer. Our case illustrates a skull base metastasis from breast cancer, detected in a diagnostic process initiated by ophthalmologic examination. CASE REPO...

Dr. Baltazar Leão Reis – Rua Romano Stochiero 34/701 30130-120 Belo Horizonte MG Brasil. E-mail: [email protected] Hemangiomas are benign vascular tumors that may involve any part of the body. Primary osseous hemangiomas occur more frequently in the spine and less commonly in the skull. Toynbee 1845 was the author of the first report in English, a case of hemangioma of the skull bones. ...

CLINICAL SCENARIO During routine staging work-up for a left breast mass, a 68-year-old woman complained of dysphagia and dysphonia. During further investigations, a left-sided lesion at the foramen magnum was observed on brain imaging. Both lesions were biopsied and showed a classical chordoma. MANAGEMENT The skull-base lesion and the breast lesion were surgically resected, and adjuvant radio...

Several cases with skull metastases hepatocellular carcinoma have so far been reported in the English literature. However, recurrent skull metastasis hepatocellular carcinoma at 2 month post operation after craniectomy and total tumor removal has never been published. We reported a 57-year-old Thai female presented with a recurrent enlarging painless left parieto-occipital skull mass after 2 mo...